Nový Brian B
Loma Linda University, USA; DentaQuest Institute, Westborough, MA 01581, USA.
J Evid Based Dent Pract. 2014 Jun;14 Suppl:27-32. doi: 10.1016/j.jebdp.2014.04.004. Epub 2014 Apr 5.
There is some evidence to support the use of salivary diagnostics in dentistry.
The use of saliva as a diagnostic fluid has the potential to shape the role of oral health care professionals in the health care system. While more than a handful of chairside diagnostic tests are available for use by private practitioners, the evidence supporting their use continues to emerge.
An electronic search of the literature indexed on the PubMed electronic database was conducted to identify human clinical trials utilizing commercially available salivary diagnostics. Papers meeting the inclusion criteria, and any applicable references were critically appraised following SORT guidelines.
While the literature concerning salivary analysis is continuously growing, the limited literature that is available doesn't focus on patient oriented health outcomes. This 'infant' literature is focused on validating metrics and identifying biomarkers with diagnostic potential. As such, the evidence level of the literature is graded as level 3. Despite the lower grade, the research in this area shows consistent results, coherent conclusions, and research identifying new biomarkers will provide additional dimensions to salivary diagnostics.
有一些证据支持在牙科中使用唾液诊断。
将唾液用作诊断液有可能改变口腔保健专业人员在医疗保健系统中的角色。虽然有超过少数几种可供私人执业者在椅旁使用的诊断测试，但支持其使用的证据仍在不断涌现。
对PubMed电子数据库中索引的文献进行电子检索，以识别使用市售唾液诊断方法的人体临床试验。符合纳入标准的论文以及任何适用的参考文献均按照SORT指南进行严格评估。
虽然有关唾液分析的文献在不断增加，但现有的有限文献并未关注以患者为导向的健康结果。这一“新兴”文献主要集中在验证指标和识别具有诊断潜力的生物标志物。因此，该文献的证据级别被评为3级。尽管级别较低，但该领域的研究结果一致、结论连贯，并且识别新生物标志物的研究将为唾液诊断提供更多维度。
