Li Zheng-hong, Dong Mei, Wang Zhi-feng
Department of Pediatrics, PUMC Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Zhonghua Er Ke Za Zhi. 2006 Feb;44(2):87-9.
To investigate the characteristics of anorectal motility spectrum in children with functional constipation in comparison with healthy children and determine the efficacy of treatment measures based on the results of anorectal manometry.
Anorectal manometric indexes were detected by the multi-functional manometry in eight patients with functional constipation aged (11.4 +/- 4.8) yrs and ten healthy children aged (10.5 +/- 3.5) yrs from May 2004 to June 2005. The patients received combined treatment including probiotics (Bifid. triple viable), prebiotics (Lactulose) and regular defecation according to the results of anorectal manometry in patients with functional constipation. The efficacy of these conservative measures were estimated during the course of treatment.
No statistical differences were found in the indexes of effective length of anal sphincter, maximal systolic pressure and the duration of more than 50% of maximal systolic pressure between two groups. But minimal sensitivity and maximal tolerated volume between the two groups were significantly different. Seven of eight patients got better with the conservative treatment.
Abnormal features exit in the anorectal motility spectrum of the children with functional constipation. The clinical efficacy of the conservative treatment measures based on the results of anorectal manometry is significantly good.
对比功能性便秘患儿与健康儿童的肛门直肠动力谱特征，并根据肛门直肠测压结果确定治疗措施的疗效。
2004年5月至2005年6月，对8例年龄为（11.4±4.8）岁的功能性便秘患儿及10例年龄为（10.5±3.5）岁的健康儿童采用多功能测压法检测肛门直肠测压指标。根据功能性便秘患儿的肛门直肠测压结果，给予益生菌（双歧三联活菌）、益生元（乳果糖）及规律排便的综合治疗。在治疗过程中评估这些保守措施的疗效。
两组间肛门括约肌有效长度、最大收缩压及最大收缩压50%以上持续时间等指标无统计学差异。但两组间最小敏感度和最大耐受容量有显著差异。8例患者中有7例经保守治疗后病情好转。
功能性便秘患儿的肛门直肠动力谱存在异常特征。基于肛门直肠测压结果的保守治疗措施临床疗效显著。
