Pushkarskaia N L, Voĭtsekhovskaia A A, Frank-Kamenetskaia I A, Bikbulatov R M, Kasparov A A
Vestn Oftalmol. 1991 Sep-Oct;107(5):43-6.
The developed method for rapid diagnosis of ophthalmic herpes is based on quantitative estimation of the results of immunofluorescent studies of the cells in scrapings off the eye conjunctiva. A total of 213 patients were examined with the use of this method; herpes simplex virus antigen was detected in 56.5%, but only in 23.5% of the examinees the antigen levels surpassed 10 and 100-fold the levels of basal virus carriership. Parallel clinical laboratory diagnostic investigations have shown that the second and third stages of the virus antigen accumulation in the conjunctival cells correlated with the severity of the clinical symptoms.
所开发的眼科疱疹快速诊断方法基于对眼结膜刮片中细胞免疫荧光研究结果的定量评估。使用该方法共检查了213例患者;56.5%的患者检测到单纯疱疹病毒抗原,但只有23.5%的受检者抗原水平超过基础病毒携带水平的10倍和100倍。并行的临床实验室诊断研究表明,结膜细胞中病毒抗原积累的第二和第三阶段与临床症状的严重程度相关。