Levi O, Waner T, Baneth G, Keysary A, Bruchim Y, Silverman J, Harrus S
Koret School of Veterinary Medicine, Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel.
J Vet Med B Infect Dis Vet Public Health. 2006 Mar;53(2):78-80. doi: 10.1111/j.1439-0450.2006.00911.x.
The presence of reacting antibodies to Anaplasma phagocytophilum has previously been demonstrated in Israel, both in humans and the golden jackal (Canis aureus syriacus). This study was undertaken to determine the seroprevalence of A. phagocytophilum antibodies in two additional potential hosts, domestic dogs and horses in order to investigate the possibility of exposure to the organism in Israel. Of 195 dogs tested, 9% were seroreactive with A. phagocytophilum antigen and 30% were seroreactive to Ehrlichia canis. Twenty-nine percent of the dogs seropositive for E. canis were also reactive to A. phagocytophilum. Two dogs had immunofluorescence antibody (IFA) antibody titres for A. phagocytophilum greater than E. canis. The equine serological survey (n = 300) revealed no seroreactive horses. The results presented in this study suggest that dogs in Israel could have been accidentally exposed to A. phagocytophilum, for example by ticks carried on migrating birds, however, the possibility of cross-reaction with E. canis should also be considered. In spite of the high prevalence of ticks on horses in Israel during the summer months, no evidence for exposure to A. phagocytophilum was apparent.
此前在以色列已证实，人类和金豺（叙利亚金豺，Canis aureus syriacus）体内存在针对嗜吞噬细胞无形体的反应性抗体。本研究旨在确定另外两种潜在宿主——家犬和马匹中嗜吞噬细胞无形体抗体的血清阳性率，以调查在以色列接触该病原体的可能性。在接受检测的195只犬中，9%对嗜吞噬细胞无形体抗原呈血清反应阳性，30%对犬埃立克体呈血清反应阳性。犬埃立克体血清阳性的犬中有29%对嗜吞噬细胞无形体也呈反应性。有两只犬针对嗜吞噬细胞无形体的免疫荧光抗体（IFA）滴度高于犬埃立克体。马匹血清学调查（n = 300）显示没有呈血清反应阳性的马匹。本研究结果表明，以色列的犬可能意外接触了嗜吞噬细胞无形体，例如通过迁徙鸟类携带的蜱虫，但也应考虑与犬埃立克体发生交叉反应的可能性。尽管在夏季以色列的马匹身上蜱虫感染率很高，但未发现明显接触嗜吞噬细胞无形体的证据。
