Kersey Thomas L, Patel Sonia, Thaller Vladamir T
Royal Eye Infirmary, Mutley Plain, Plymouth, UK.
Clin Exp Ophthalmol. 2006 Mar;34(2):152-5. doi: 10.1111/j.1442-9071.2006.01173.x.
To compare the first-throw tension holding property of two braided absorbable sutures commonly used in oculoplastic surgery.
The study was an in vitro experimental model. 6/0 Polyglycolic acid (Dexon S) and 6/0 Polyglactin 910 (Coated Vicryl) were compared using an experimental model to determine first-throw knot security. A polypropylene suture (Surgipro 2) was included as a benchmark to judge the apparatus by, ensuring that our experiment could be designed independently of the test suture materials. Increasing metric loads were applied to the first double throw of a surgical knot. Each suture was tested to the point of knot slipping and the critical tension recorded. All the sutures were kept wet during use. Three variations of the experiment were undertaken: experiment 1 -- two metal loops brought together by the test suture; experiment 2 -- two strips of tissue brought together by the test suture; and experiment 3 -- a knot tied over a metal bar coated in tissue. The tissue used was processed cross-linked porcine dermal collagen (Permacol). Each experiment was repeated three times for each suture type and the mean value taken.
Experiment 1: Dexon S 12.2 g (11, 12, 13.5), Coated Vicryl 2.5 g (2.5, 2.5, 2.5) and Surgipro 2 2.3 g (2, 2, 3); experiment 2: Dexon S 33.33 g (30, 35, 35), Coated Vicryl 25 g (25, 25, 25) and Surgipro 2 5 g (5, 5, 5); experiment 3: Dexon S 100 g (100, 100, 100), Coated Vicryl 56.667 g (60, 55, 55) and Surgipro 2 5 g (5, 5, 5).
Dexon S-braided absorbable suture has significantly better first-throw knot security when compared with Coated Vicryl. This is an important property when suturing tissues under tension as it minimizes slippage before the locking throw is tied.
比较眼部整形手术中常用的两种编织可吸收缝线的首次打结张力保持性能。
本研究采用体外实验模型。使用实验模型比较6/0聚乙醇酸（Dexon S）和6/0聚乳酸910（涂层薇乔），以确定首次打结的牢固程度。纳入聚丙烯缝线（Surgipro 2）作为基准来评判实验装置，确保我们的实验设计可独立于测试缝线材料。对手术结的第一个双结施加逐渐增加的公制负荷。对每种缝线测试至结滑动点，并记录临界张力。所有缝线在使用过程中保持湿润。进行了三种实验变体：实验1——通过测试缝线将两个金属环拉拢；实验2——通过测试缝线将两条组织条拉拢；实验3——在涂有组织的金属棒上打结。所用组织为经处理的交联猪真皮胶原蛋白（Permacol）。每种缝线类型的每个实验重复三次，并取平均值。
实验1：Dexon S为12.2克（11、12、13.5），涂层薇乔为2.5克（2.5、2.5、2.5），Surgipro 2为2.3克（2、2、3）；实验2：Dexon S为33.33克（30、35、35），涂层薇乔为25克（25、25、25），Surgipro 2为5克（5、5、5）；实验3：Dexon S为100克（100、100、100），涂层薇乔为56.667克（60、55、55），Surgipro 2为5克（5、5、5）。
与涂层薇乔相比，Dexon S编织可吸收缝线的首次打结牢固程度明显更好。在张力下缝合组织时，这是一项重要特性，因为它可在打锁定结之前将滑动降至最低。
