Bourne R B, Bitar H, Andreae P R, Martin L M, Finlay J B, Marquis F
Division of Orthopedic Surgery, University Hospital, University of Western Ontario, London.
Can J Surg. 1988 Jan;31(1):43-5.
Absorbable sutures are initially equal or superior to nonabsorbable sutures in terms of tensile strength but are absorbed at variable rates by the action of hydrolysis. This study demonstrated that the in-vivo half-life tensile strength of the braided absorbable sutures polyglycolic acid (Dexon Plus) and polyglactin 910 (Vicryl) is 2 weeks, whereas those of the monofilament absorbable sutures polyglyconate (Maxon) and polydioxanone (PDS) are 3 and 6 weeks respectively. The addition of a single hitch or six knots reduced the in-vitro tensile strength by 30% to 35%. Polyglyconate (Maxon) suture demonstrated the best in-vitro knot security.
可吸收缝线在拉伸强度方面最初等同于或优于不可吸收缝线，但会通过水解作用以不同速率被吸收。本研究表明，编织可吸收缝线聚乙醇酸（德克松加强型）和聚乙交酯910（薇乔）的体内拉伸强度半衰期为2周，而单丝可吸收缝线聚甘醇酸酯（马克松）和聚二氧六环酮（PDS）的半衰期分别为3周和6周。添加一个单结或六个结会使体外拉伸强度降低30%至35%。聚甘醇酸酯（马克松）缝线在体外打结安全性方面表现最佳。
