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Prophylactic perioperative antiviral therapy for LASIK in patients with inactive herpetic keratitis.

作者信息

de Rojas Silva Ma Victoria, Díez-Feijóo Elío, Javaloy Jaime, Sánchez-Salorio Manuel

机构信息

Fundación Instituto Galego de Oftalmoloxía, Universidad de Santiago de Compostela, Spain.

出版信息

J Refract Surg. 2006 Apr;22(4):404-6. doi: 10.3928/1081-597X-20060401-19.

DOI:10.3928/1081-597X-20060401-19
PMID:16629075
Abstract

PURPOSE

To report the outcome of LASIK in patients with inactive herpetic keratitis in which perioperative antiviral prophylaxis was used to prevent the recurrence of ocular herpes.

METHODS

We report an uncontrolled series of five patients with inactive herpetic keratitis for at least 1 year before surgery in whom LASIK was successfully performed. All patients showed normal topography, pachymetry, and corneal sensitivity with no central corneal scarring. Perioperative prophylaxis was used in each case with oral valacyclovir and topical acyclovir ointment.

RESULTS

None of the eyes developed reactivation of herpetic keratitis during follow-up.

CONCLUSIONS

This study suggests that perioperative antiviral prophylaxis may protect the cornea from herpes simplex virus reactivation after LASIK.

摘要

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