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准分子激光原位角膜磨镶术和准分子激光角膜切削术后的疱疹性内皮炎

Herpes endotheliitis following laser-assisted keratomileusis and photorefractive keratectomy.

作者信息

Moshirfar Majid, Ziari Melody, Peterson Christian, Kelkar Neil, Ronquillo Yasmyne, Hoopes Phillip

机构信息

Hoopes Vision Research Center, Hoopes Vision, Draper, Murray, UT, USA.

John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City, Murray, UT, USA.

出版信息

Taiwan J Ophthalmol. 2023 Feb 20;13(1):93-96. doi: 10.4103/tjo.TJO-D-22-00156. eCollection 2023 Jan-Mar.

DOI:10.4103/tjo.TJO-D-22-00156
PMID:37252172
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10220447/
Abstract

Herpes endotheliitis is a less common manifestation of herpes keratitis, and characteristic examination findings include corneal edema and the presence of keratic precipitates. Infection may be primary or secondary to herpes virus reactivation following exposure to a potential trigger such as physiologic stress or environmental factors. Ocular surgery, including laser-assisted keratomileusis (LASIK) and photorefractive keratectomy (PRK), can trigger reactivation in patients with or without a documented history of previous herpes infection. We present two patients with visually insignificant stromal scarring who denied a previous history of herpetic disease and developed herpes endotheliitis following LASIK and PRK. We demonstrate the importance of an appropriately thorough preoperative evaluation and further workup of any corneal abnormalities, even if such findings initially appear inconsequential.

摘要

疱疹性内皮炎是疱疹性角膜炎较少见的一种表现形式,其特征性检查结果包括角膜水肿和角膜后沉着物的出现。感染可能是原发性的,也可能是在接触潜在诱因(如生理应激或环境因素)后疱疹病毒再激活继发的。眼科手术,包括准分子激光原位角膜磨镶术(LASIK)和准分子激光屈光性角膜切削术(PRK),可在有或无既往疱疹感染记录史的患者中引发病毒再激活。我们报告了两名基质瘢痕对视力影响不大的患者,他们否认有疱疹病史,在接受LASIK和PRK后发生了疱疹性内皮炎。我们证明了进行适当全面的术前评估以及对任何角膜异常进行进一步检查的重要性,即使这些发现最初看似无关紧要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7298/10220447/b1f598eb4334/TJO-13-93-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7298/10220447/319cb19b0a66/TJO-13-93-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7298/10220447/58e841b18dac/TJO-13-93-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7298/10220447/0cd3f448b1dd/TJO-13-93-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7298/10220447/b1f598eb4334/TJO-13-93-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7298/10220447/319cb19b0a66/TJO-13-93-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7298/10220447/58e841b18dac/TJO-13-93-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7298/10220447/0cd3f448b1dd/TJO-13-93-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7298/10220447/b1f598eb4334/TJO-13-93-g004.jpg

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Clin Exp Optom. 2021 Apr;104(3):396-405. doi: 10.1080/08164622.2021.1877531. Epub 2021 Feb 24.
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Corneal Refractive Surgery in Patients with a History of Herpes Simplex Keratitis: A Narrative Review.有单纯疱疹性角膜炎病史患者的角膜屈光手术:一项叙述性综述
Clin Ophthalmol. 2020 Nov 16;14:3891-3901. doi: 10.2147/OPTH.S282070. eCollection 2020.
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Ocular surgery after herpes simplex and herpes zoster keratitis.
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Int Ophthalmol. 2020 Dec;40(12):3599-3612. doi: 10.1007/s10792-020-01539-6. Epub 2020 Sep 10.
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Pathogenesis of herpes simplex keratitis: The host cell response and ocular surface sequelae to infection and inflammation.单纯疱疹性角膜炎的发病机制:感染和炎症对宿主细胞的反应和眼表面后遗症。
Ocul Surf. 2019 Jan;17(1):40-49. doi: 10.1016/j.jtos.2018.10.002. Epub 2018 Oct 11.
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