Yoo Nam-Hee, Kim Jong-Pyung, Yun Bong-Sik, Ryoo In-Ja, Lee In-Kyoung, Yoon Eui-Soo, Koshino Hiroyuki, Yoo Ick-Dong
Laboratory of Antioxidants, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305333, Korea.
J Antibiot (Tokyo). 2006 Feb;59(2):110-3. doi: 10.1038/ja.2006.16.
New sesquiterpenes, hirsutenols D-F, were isolated from the fermentation broth of Stereum hirsutum, and their structures were determined on the basis of various spectroscopic analyses. Hirsutenols E and F showed significant scavenging activity against superoxide anion radicals with EC50 values of 1.62 and 0.39 mM, respectively.