Rasova K, Havrdova E, Brandejsky P, Zálisová M, Foubikova B, Martinkova P
Department of Neurology, 1st Medical Faculty, Charles University in Prague and General Faculty Hospital, Czech Republic.
Mult Scler. 2006 Apr;12(2):227-34. doi: 10.1191/135248506ms1248oa.
The aim of this study was to compare the effect of four different programmes on spiroergometric, spirometric and clinical parameters in multiple sclerosis (MS) patients.
One hundred and twelve MS patients were divided into four groups. The first group underwent neurophysiologically based physiotherapy, the second aerobic training, the third combined therapy (neurophysiologically based physiotherapy and aerobic training) and the fourth did not change any habits. Seventeen patients did not finish the study. Patients were examined on impairment (Expanded Disability Status Scale), disability (Barthel Index), handicap (Environment Status Scale), quality of life (Multiple Sclerosis Quality of Life), fatigue (Modified Fatigue Impact Scale), depression (Beck Depression Inventory Score), respiratory function (spirometric parameters on spirometry) and physical fitness (spiroergometric parameters on a bicycle ergometer).
The patients who participated in one of our training programmes showed a significant improvement of the examined parameters in comparison to those who did not change their present habits. Each of the four training programmes had a different impact on the parameters, which means that each of them had a different effect. The neurophysiologically based physiotherapy had the greatest impact on impairment, and the aerobic training on spirometric and spiroergometric parameters. All methods (the neurophysiologically based physiotherapy, the aerobic training and the combined programme) had an impact on fatigue.
本研究旨在比较四种不同方案对多发性硬化症(MS)患者的运动心肺功能、肺功能和临床参数的影响。
112例MS患者被分为四组。第一组接受基于神经生理学的物理治疗,第二组进行有氧训练,第三组接受联合治疗(基于神经生理学的物理治疗和有氧训练),第四组不改变任何习惯。17例患者未完成研究。对患者进行了以下方面的检查:损伤(扩展残疾状态量表)、残疾(巴氏指数)、障碍(环境状态量表)、生活质量(多发性硬化症生活质量)、疲劳(改良疲劳影响量表)、抑郁(贝克抑郁量表评分)、呼吸功能(肺功能检查中的肺功能参数)和体能(自行车测力计上的运动心肺功能参数)。
与未改变现有习惯的患者相比,参与我们其中一项训练方案的患者在检查参数方面有显著改善。四个训练方案中的每一个对参数都有不同的影响,这意味着它们各自产生了不同的效果。基于神经生理学的物理治疗对损伤影响最大,有氧训练对肺功能和运动心肺功能参数影响最大。所有方法(基于神经生理学的物理治疗、有氧训练和联合方案)都对疲劳有影响。