一名21岁男性患成人T细胞白血病/淋巴瘤。

Adult T-cell leukemia/lymphoma in a 21-year-old man.

作者信息

Owatari Satsuki, Uozumi Kimiharu, Tokunaga Masahito, Tokunaga Mayumi, Haraguchi Kouichi, Suzuki Shinsuke, Arima Naomichi

机构信息

Department of Hematology and Immunology, Kagoshima University, Sakuragaoka, Kagoshima, Japan.

出版信息

Clin Lab Haematol. 2006 Apr;28(2):141-4. doi: 10.1111/j.1365-2257.2006.00764.x.

DOI:10.1111/j.1365-2257.2006.00764.x

PMID:16630222

Abstract

Adult T-cell leukemia/lymphoma (ATL) is malignancy of mature T cells that caused by infection with human T-cell leukemia virus type I (HTLV-I). Leukemogenesis of ATL cells considered to involve a multistep oncogenic process, resulting in a very long latency period. But, we report here the case of a 21-year-old man having suffered from recurrent stomatititis who has already developed acute-type ATL. ATL generally occurs after a long latency period, and the present case in a young man is thus very rare.

摘要

成人T细胞白血病/淋巴瘤（ATL）是由I型人类T细胞白血病病毒（HTLV-I）感染引起的成熟T细胞恶性肿瘤。ATL细胞的白血病发生被认为涉及一个多步骤的致癌过程，导致很长的潜伏期。但是，我们在此报告一例21岁患有复发性口腔炎且已发展为急性型ATL的男性病例。ATL通常在很长的潜伏期后发生，因此该年轻男性的病例非常罕见。