Reyss A-C, Proust-Richard C, Catteau-Jonard S, Dewailly D
Service de Gynécologie Endocrinienne et Médecine de la Reproduction, Hôpital Jeanne-de-Flandre, CHRU de Lille, 2, avenue Oscar-Lambret, 59037 Lille cedex, France.
Gynecol Obstet Fertil. 2006 Apr;34(4):341-6. doi: 10.1016/j.gyobfe.2006.02.017. Epub 2006 Apr 21.
The polycystic ovary syndrome (PCOS) is the most frequent cause of hyperandrogenism and anovulation in adult women as well as in adolescent girls. Since 2003 the diagnosis of PCOS has been based on the association of hyperandrogenism, oligoanovulation and polycystic ovary (PCO) morphology at ultrasound (at least 2 items out of 3). In adolescents however, PCOS features may be difficult to distinguish from the symptoms of the end of puberty. Moreover, transvaginal ultrasound examination is seldom possible, and it is difficult to get precise imaging of the ovaries by abdominal route. However, the diagnosis of PCOS in a hyperandrogenic and/or oligomenorrheic adolescent requires on the strict application of the Rotterdam criteria, as in adult women. Priority should be given to clinical features whereas pelvic ultrasound must be considered as optional. Few hormonal assays will serve mainly to make the differential diagnosis, in addition to clinical findings. Once established, the diagnosis of PCOS in an adolescent girl must lead to the detection of the metabolic syndrome by means of simple investigations. This will allow early prevention of its complications.
多囊卵巢综合征（PCOS）是成年女性以及青春期女孩高雄激素血症和无排卵的最常见原因。自2003年以来，PCOS的诊断基于高雄激素血症、稀发排卵和多囊卵巢（PCO）超声形态学表现（三项中至少两项）。然而，在青少年中，PCOS的特征可能难以与青春期末期的症状区分开来。此外，很少能进行经阴道超声检查，通过腹部途径很难获得卵巢的精确图像。然而，对于高雄激素血症和/或月经稀发的青少年，PCOS的诊断需要严格应用鹿特丹标准，如同成年女性一样。应优先考虑临床特征，而盆腔超声检查可视为可选项目。除临床检查结果外，很少的激素检测主要用于鉴别诊断。一旦确诊，青春期女孩的PCOS诊断必须通过简单检查来检测代谢综合征。这将有助于早期预防其并发症。
