al-Fouzan A S, al Saleh Q A, Najem N M, Rostom A I
Department of Dermatology, Al-Sabah Hospital, Safat, Kuwait.
Int J Dermatol. 1991 Jul;30(7):519-21. doi: 10.1111/j.1365-4362.1991.tb04878.x.
Twenty-four patients suffering from single or multiple lesions of cutaneous leishmaniasis were included in this study. Most of the lesions were on the extremities. The patients were randomly divided into two groups. Most of the patients in the first group who were given oral itraconazole for a period of 6-8 weeks showed excellent clinical response. On the other hand, only one patient in the second control group who was given placebo showed good clinical improvement. Systemically administered itraconazole may prove to be a valuable modality for the treatment of cutaneous leishmaniasis.
本研究纳入了24例患有皮肤利什曼病单发或多发皮损的患者。大多数皮损位于四肢。患者被随机分为两组。第一组大多数患者口服伊曲康唑6 - 8周，临床反应良好。另一方面，第二对照组中仅1例服用安慰剂的患者临床有较好改善。全身应用伊曲康唑可能被证明是治疗皮肤利什曼病的一种有价值的方法。
