Sörös Peter, Sokoloff Lisa Guttman, Bose Arpita, McIntosh Anthony R, Graham Simon J, Stuss Donald T
Imaging Research, Sunnybrook and Women's College Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada.
Neuroimage. 2006 Aug 1;32(1):376-87. doi: 10.1016/j.neuroimage.2006.02.046. Epub 2006 May 2.
To investigate the neural network of overt speech production, event-related fMRI was performed in 9 young healthy adult volunteers. A clustered image acquisition technique was chosen to minimize speech-related movement artifacts. Functional images were acquired during the production of oral movements and of speech of increasing complexity (isolated vowel as well as monosyllabic and trisyllabic utterances). This imaging technique and behavioral task enabled depiction of the articulo-phonologic network of speech production from the supplementary motor area at the cranial end to the red nucleus at the caudal end. Speaking a single vowel and performing simple oral movements involved very similar activation of the cortical and subcortical motor systems. More complex, polysyllabic utterances were associated with additional activation in the bilateral cerebellum, reflecting increased demand on speech motor control, and additional activation in the bilateral temporal cortex, reflecting the stronger involvement of phonologic processing.
为研究明显言语产生的神经网络，对9名年轻健康成年志愿者进行了事件相关功能磁共振成像（fMRI）。选择了一种集群图像采集技术，以尽量减少与言语相关的运动伪影。在进行口腔运动以及越来越复杂的言语（孤立元音以及单音节和三音节发音）时采集功能图像。这种成像技术和行为任务能够描绘出从颅端的辅助运动区到尾端的红核的言语产生的关节-音韵网络。说出单个元音和进行简单口腔运动涉及皮质和皮质下运动系统非常相似的激活。更复杂的多音节发音与双侧小脑的额外激活相关，这反映了对言语运动控制的需求增加，以及双侧颞叶皮质的额外激活，这反映了音韵处理更强的参与。
