García José R, Simo Marc, Huguet Marina, Ysamat Montserrat, Lomeña Francisco
CETIR Unitat PET, Barcelona, Spain.
Clin Transl Oncol. 2006 Feb;8(2):124-8. doi: 10.1007/s12094-006-0169-7.
Retrospectively analysed our experience in Renal Cell carcinoma (RCC) patients studied with 18-Fluorodeoxyglucose Positron Emission Tomography (FDG PET) to rule out the incidence and clinical impact of heart metastases.
In two years, 37 patients with RCC were studied with FDG PET. 10 were studied for initial staging and 27 patients were evaluated for suspected recurrence or re-staging.
In two patients (5%), PET scan showed pathological focal uptake in myocardium. On the bases of this finding, MRI was performed visualizing a myocardial mass in both lesions and confirmed by histology in one of them. The hypothesis of prolepses of the tumour by thrombus in RCC patients justified the surgery.
Whole-body FDG PET in RCC patients could help to diagnose cardiac metastasis, and allows the possibility of therapeutic surgery, due to the thrombus significance of heart involvement.
回顾性分析我们对肾细胞癌(RCC)患者进行18氟脱氧葡萄糖正电子发射断层扫描(FDG PET)以排除心脏转移的发生率及其临床影响的经验。
两年内,对37例RCC患者进行了FDG PET检查。10例用于初始分期研究,27例因怀疑复发或重新分期接受评估。
2例患者(5%)的PET扫描显示心肌有病理局灶性摄取。基于这一发现,进行了MRI检查,在两个病灶中均发现了心肌肿块,其中1例经组织学证实。RCC患者肿瘤因血栓形成而提前转移的假说证明了手术的合理性。
RCC患者的全身FDG PET有助于诊断心脏转移,并由于心脏受累的血栓意义而使治疗性手术成为可能。