Gorbach Christoph, Schmid Marius R, Elfering Achim, Hodler Juerg, Boos Norbert
Center for Spinal Surgery, University of Zurich, University Hospital Balgrist, Zurich, Switzerland.
AJR Am J Roentgenol. 2006 May;186(5):1228-33. doi: 10.2214/AJR.04.1042.
The objective of our study was to investigate outcome predictors of short- and medium-term therapeutic efficacy of facet joint blocks.
Forty-two patients with chronic lower back pain who were undergoing facet joint blocks at one (n = 29) or two (n = 13) levels were analyzed. All patients underwent MRI or CT of the lumbar spine within 5 months before the facet joint blocks. The facet joint blocks were performed under fluoroscopic guidance. A small amount (< 0.3 mL) of iodinated contrast agent, 0.5 mL of local anesthetics and 0.5 mL of steroids, were injected. The initial pain response was prospectively assessed using a visual analogue scale. Additional data, including short-term effect (> 1 week) and medium-term effect (> 3 months), were collected by a structured telephone interview. CT and MRI were reviewed with regard to the extent of facet joint abnormalities. Multiple logistic regression analyses were conducted to identify outcome predictor for efficacy of facet joint blocks.
A positive immediate effect was seen in 31 patients (74%). A positive medium-term effect was found in 14 patients (33%). Pain alleviated by motion (p = 0.035) and the absence of joint-blocking sensation (p = 0.042) predicted pain relief. However, the extent of facet joint osteoarthritis on MRI and CT was not a significant predictor for outcome (p = 0.57-0.95).
Facet joint blocks appear to have a beneficial medium-term effect in one third of patients with chronic lower back pain and may therefore be a reasonable adjunct to nonoperative treatment. However, outcome appears to depend on clinical, not on morphologic, imaging findings.
本研究的目的是调查小关节阻滞短期和中期治疗效果的预后预测因素。
分析了42例正在接受单节段(n = 29)或双节段(n = 13)小关节阻滞的慢性下腰痛患者。所有患者在小关节阻滞前5个月内均接受了腰椎MRI或CT检查。小关节阻滞在透视引导下进行。注射少量(<0.3 mL)碘化造影剂、0.5 mL局部麻醉剂和0.5 mL类固醇。使用视觉模拟量表前瞻性评估初始疼痛反应。通过结构化电话访谈收集包括短期效果(>1周)和中期效果(>3个月)在内的其他数据。回顾CT和MRI以了解小关节异常的程度。进行多因素逻辑回归分析以确定小关节阻滞疗效的预后预测因素。
31例患者(74%)出现即时阳性效果。14例患者(33%)出现中期阳性效果。运动时疼痛减轻(p = 0.035)和无关节阻滞感(p = 0.042)可预测疼痛缓解。然而,MRI和CT上小关节骨关节炎的程度不是预后的显著预测因素(p = 0.57 - 0.95)。
小关节阻滞似乎对三分之一的慢性下腰痛患者有有益的中期效果,因此可能是一种合理的非手术治疗辅助方法。然而,治疗效果似乎取决于临床因素,而非形态学影像学表现。