Park Jun-Young, Kim Doo-Hwan, Seo Dong-Kyun, Yoon Syn-Hae, Lee Gunn, Lee Sukyung, Park Chan-Hye, Sim Sung Eun, Suh Jeong-Hun
Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
Department of Anesthesiology and Pain Medicine, Jun Orthopedic Hospital, Seoul 04790, Korea.
J Clin Med. 2019 Apr 19;8(4):538. doi: 10.3390/jcm8040538.
The aim of this study was to determine the association between radiologic spinal pathology and the response to medial branches block (MBB). This retrospective observational study compared 165 patients. A successful response was defined as ≥30% or a 2-point reduction in the numeric rating scale (NRS) compared with the baseline at the 1-month follow-up. The facet angle, facet angle difference, facet joint degeneration, disc height and spondylolisthesis grade were analyzed from an MRI at the L3 to S1 levels. Univariate and multivariate logistic regression analyses were used to evaluate independent factors associated with a successful response of MBB. In the univariate analysis, the disc height at L5-S1 and facet angle difference at L3-4 were lower in the positive responders ( = 0.022 and = 0.087, respectively). In the multivariate analysis, the facet angle difference at L3-4 and disc height at L5-S1 were independent factors associated with a successful response (odds ratio = 0.948; = 0.038 and odds ratio = 0.864; = 0.038, respectively). In patients with a degenerative disc at L5-S1, MBB can lead to a good response for at least one month. In patients with facet tropism at L3-4 level, the response to MBB after one month is likely to be poor.
本研究的目的是确定脊柱放射学病理与内侧支阻滞(MBB)反应之间的关联。这项回顾性观察性研究比较了165例患者。成功反应定义为与1个月随访时的基线相比,数字评分量表(NRS)降低≥30%或降低2分。从L3至S1水平的MRI分析小关节角度、小关节角度差异、小关节退变、椎间盘高度和椎体滑脱分级。采用单因素和多因素逻辑回归分析来评估与MBB成功反应相关的独立因素。在单因素分析中,阳性反应者L5-S1的椎间盘高度和L3-4的小关节角度差异较低(分别为P = 0.022和P = 0.087)。在多因素分析中,L3-4的小关节角度差异和L5-S1的椎间盘高度是与成功反应相关的独立因素(优势比分别为0.948;P = 0.038和优势比为0.864;P = 0.038)。在L5-S1椎间盘退变的患者中,MBB可导致至少1个月的良好反应。在L3-4水平存在小关节不对称的患者中,1个月后对MBB的反应可能较差。