Schubert Armin, Deogaonkar Anupa, Drummond John C
Department of Anesthesiology, The University of California at San Diego, La Jolla, CA 92093, USA.
Anesth Analg. 2006 May;102(5):1543-7. doi: 10.1213/01.ane.0000198665.84248.61.
Verification of appropriate precordial Doppler probe position over the anterior chest wall is crucial for early detection of venous air embolism. We studied responses to normal saline (NS) and carbon dioxide (CO2) test injections at various probe locations during elective craniotomy. All patients received four IV injections (10 mL of NS and 1 mL of CO2 via central and peripheral venous catheters). Doppler sounds were simultaneously recorded with two separate probes. In Group A, probes were placed in left and right parasternal positions. In Group B, the left probe was intentionally malpositioned as far laterally over the left precordium as was compatible with an audible signal. In Group A (n = 23), a left parasternal Doppler signal was easily obtainable in 23 of 23 patients, versus 18 of 23 patients for the right parasternal probe (P < 0.05). In Group B (n = 17), central CO2 injection yielded a positive right parasternal response rate of 88% compared with 29% over the far left precordium (P < 0.015), where central NS injections yielded a 76% response rate (P < 0.015 versus central CO2 injection). Left parasternal placement is at least as sensitive to clinical venous air embolism events as right parasternal placement. Peripheral saline injection represents a viable alternative (83% response rate). Vigorous central injection of 10 mL of NS however, risks false positive verification of left lateral precordial probe placement.
在前胸壁上确认心前区多普勒探头的合适位置对于早期发现静脉空气栓塞至关重要。我们研究了在择期开颅手术期间,在不同探头位置对生理盐水(NS)和二氧化碳(CO₂)试验注射的反应。所有患者均接受了四次静脉注射(通过中心静脉导管和外周静脉导管分别注射10 mL NS和1 mL CO₂)。用两个独立的探头同时记录多普勒声音。A组中,探头置于左、右胸骨旁位置。B组中,将左侧探头故意放置在左心前区尽可能外侧的位置,只要能获得可听信号即可。在A组(n = 23)中,23例患者中有23例很容易获得左胸骨旁多普勒信号,而右胸骨旁探头在23例患者中有18例可获得信号(P < 0.05)。在B组(n = 17)中,中心注射CO₂时,右胸骨旁的阳性反应率为88%,而在左心前区最外侧为29%(P < 0.015),中心注射NS时,左心前区最外侧的反应率为76%(与中心注射CO₂相比,P < 0.015)。左胸骨旁放置对临床静脉空气栓塞事件的敏感性至少与右胸骨旁放置相同。外周注射生理盐水是一种可行的替代方法(反应率为83%)。然而,强力中心注射10 mL NS有导致左心前区外侧探头放置假阳性确认的风险。