Newman Jeffrey D, Setford Steven J
Institute of BioScience and Technology, Cranfield University, Silsoe, Bedfordshire MK45 4DT, United Kingdom.
Mol Biotechnol. 2006 Mar;32(3):249-68. doi: 10.1385/MB:32:3:249.
The biosensor field has grown enormously since the first demonstration of the biosensor concept by Leland C. Clark, Jr. in 1962. Today's biosensor market is dominated by glucose biosensors, mass-produced enzyme electrodes for the rapid self-diagnosis of blood glucose levels by diabetes sufferers. Here we take a historical look at the inception, growth, and development of the enzyme biosensor field from a commercial viewpoint. The current status of the technology is evaluated and future trends in this dynamic and fast-moving field are also anticipated.
自1962年小利兰·C·克拉克首次展示生物传感器概念以来,生物传感器领域得到了巨大发展。如今的生物传感器市场由葡萄糖生物传感器主导,它是为糖尿病患者快速自我诊断血糖水平而大量生产的酶电极。在此,我们从商业角度对酶生物传感器领域的起源、发展和成长进行历史回顾。评估了该技术的当前状况,并展望了这个充满活力且发展迅速的领域的未来趋势。