van Schil P E, Knaepen P J, Brutel de la Rivière A, van Swieten H A, Vanderschueren R G
Department of Thoracic Surgery, Antoniushospital, Nieuwegein, The Netherlands.
Eur J Cardiothorac Surg. 1991;5(11):588-91. doi: 10.1016/1010-7940(91)90225-9.
From June 1987 to June 1990, an anterior mediastinotomy with opening of the pericardium was performed in 11 patients (mean age 67.8 years) to evaluate resectability of left-sided centrally located bronchogenic carcinoma. In 3 patients (27.3%), extensive intrapericardial involvement was found which precluded complete resection. Intrapericardial extension without complete invasion of the pulmonary vessels was present in 2 patients (18.2%) who subsequently underwent an intrapericardial pneumonectomy. In 6 patients (54.5%), no intrapericardial tumour was present. There was no perioperative mortality. One patient required redrainage of the pleural cavity because of a postoperative pneumothorax. In total, 4 patients (36.4%) underwent intrapericardial pneumonectomy, 6 (54.5%) were treated by radiotherapy and 1 (9.1%) by chemotherapy. In left-sided, centrally located tumours, opening the pericardium during anterior mediastinotomy yields additional information about the degree of tumour invasion and the feasibility of performing an intrapericardial pneumonectomy. In this way, an exploratory thoracotomy is avoided and the risk of irresectability is greatly reduced.
1987年6月至1990年6月期间,对11例患者(平均年龄67.8岁)进行了前纵隔切开术并打开心包,以评估左侧中央型支气管肺癌的可切除性。3例患者(27.3%)发现心包内广泛受累,无法进行完整切除。2例患者(18.2%)存在心包内扩展但未完全侵犯肺血管,随后接受了心包内肺切除术。6例患者(54.5%)心包内无肿瘤。无围手术期死亡。1例患者因术后气胸需要再次引流胸腔。总共4例患者(36.4%)接受了心包内肺切除术,6例(54.5%)接受了放射治疗,1例(9.1%)接受了化疗。对于左侧中央型肿瘤,在前纵隔切开术期间打开心包可提供有关肿瘤侵犯程度和进行心包内肺切除术可行性的额外信息。通过这种方式,避免了开胸探查,大大降低了不可切除的风险。