Jiao X, Magistrelli P, Goldstraw P
Hubei Cancer Hospital, Wuhan, Hubel, People's Republic of China.
Eur J Cardiothorac Surg. 1997 Mar;11(3):450-4. doi: 10.1016/s1010-7940(96)01083-4.
From January 1990 to July 1994, 85 patients who were otherwise thought to have an operable tumour within the left upper lobe underwent left anterior mediastinotomy supplemented by cervical mediastinoscopy in 75 cases. This combined approach allowed assessment of nodal involvement within the superior and anterior mediastinal areas, the detection of direct tumour invasion into the mediastinum and the determination of resectability by bidigital examination of the area around the aortic arch and sub-aortic fossa.
It was found that 27 (31.8%) patients were inoperable, either because of nodal involvement at cervical mediastinoscopy (4 patients) or because of extension into the mediastinum at left anterior mediastinotomy (14 patients), or because of positive results from both methods (9 patients). The inoperability determined by this examination for patients with adenocarcinoma (8/18, 44.4%) is higher than for patients with squamous carcinoma (12/52, 23.1%). All of the 58 patients with negative findings proceeded to thoracotomy and complete resection was possible in 54 patients (93.1%).
We conclude that this combined approach is better than using either technique alone in the preoperative staging and the evaluation of resectability of left upper lobe tumours.
1990年1月至1994年7月,85例被认为左上叶有可手术切除肿瘤的患者接受了左前纵隔切开术,其中75例辅以颈部纵隔镜检查。这种联合方法可评估上纵隔和前纵隔区域的淋巴结受累情况,检测肿瘤是否直接侵犯纵隔,并通过双手触诊主动脉弓和主动脉下窝周围区域来确定肿瘤的可切除性。
发现27例(31.8%)患者无法进行手术,原因包括颈部纵隔镜检查发现淋巴结受累(4例)、左前纵隔切开术发现肿瘤侵犯纵隔(14例)或两种方法检查结果均为阳性(9例)。腺癌患者(8/18,44.4%)经该检查确定的不可切除率高于鳞癌患者(12/52,23.1%)。58例检查结果为阴性的患者均进行了开胸手术,54例(93.1%)患者成功进行了完整切除。
我们得出结论,在术前分期以及评估左上叶肿瘤的可切除性方面,这种联合方法比单独使用任何一种技术都更好。