Schwarz Frank, Bieling Katrin, Nuesry Enaas, Sculean Anton, Becker Jürgen
Department of Oral Surgery, Heinrich Heine University, Düsseldorf, Germany.
Lasers Surg Med. 2006 Aug;38(7):663-71. doi: 10.1002/lsm.20347.
The aim of the present study was to assess clinical and histo-pathological healing pattern of peri-implantitis lesions following non-surgical treatment with an Er:YAG laser (ERL).
STUDY DESIGN/MATERIALS AND METHODS: Twelve patients suffering from peri-implantitis (n = 12 implants) received a single episode of non-surgical instrumentation using ERL (12.7 J/cm2). Assessment of clinical parameters (plaque index (PI), bleeding on probing (BOP), probing pocket depth, gingival recession (GR), and clinical attachment level (CAL)), surgical defect examination, and histo-pathological examination of peri-implant tissue biopsies was performed after 1, 3, 6, 9, 12, and 24 months.
All patients exhibited improvements of all clinical parameters investigated. However, histo-pathological examination of tissue biopsies revealed a mixed chronic inflammatory cell infiltrate (macrophages, lymphocytes, and plasma cells) which seemed to be encapsulated by deposition of irregular bundles of fibrous connective tissue showing increased proliferation of vascular structures.
It was concluded that a single course of non-surgical treatment of peri-implantitis using ERL may not be sufficient for the maintenance of failing implants.
本研究旨在评估用铒激光（ERL）进行非手术治疗后种植体周围炎病变的临床和组织病理学愈合模式。
研究设计/材料与方法：12例种植体周围炎患者（共12颗种植体）接受了单次使用ERL（12.7 J/cm²）的非手术器械治疗。在1、3、6、9、12和24个月后，对临床参数（菌斑指数（PI）、探诊出血（BOP）、探诊袋深度、牙龈退缩（GR）和临床附着水平（CAL））进行评估，对手术缺损进行检查，并对种植体周围组织活检进行组织病理学检查。
所有患者的所有研究临床参数均有改善。然而，组织活检的组织病理学检查显示有混合性慢性炎性细胞浸润（巨噬细胞、淋巴细胞和浆细胞），似乎被不规则纤维结缔组织束的沉积所包裹，显示血管结构增殖增加。
得出的结论是，单次使用ERL对种植体周围炎进行非手术治疗可能不足以维持失败的种植体。
