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猫的结外结膜霍奇金样淋巴瘤

Extranodal conjunctival Hodgkin's-like lymphoma in a cat.

作者信息

Holt Elaine, Goldschmidt Michael H, Skorupski Katherine

机构信息

The Royal Veterinary College, University of London, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, United Kingdom.

出版信息

Vet Ophthalmol. 2006 May-Jun;9(3):141-4. doi: 10.1111/j.1463-5224.2006.00451.x.

Abstract

A seven-year-old female spayed Domestic Short-haired cat was brought for examination following a four-month history of conjunctivitis in the right eye. The superior palpebral conjunctiva was diffusely swollen and firm, displacing the right globe ventrally and preventing full closure of the eyelids. The right popliteal lymph node was enlarged as were several other peripheral lymph nodes. An incisional biopsy of the conjunctival swelling revealed a lymphoid neoplasm, the cellular make up of which suggested features of feline Hodgkin's-like lymphoma. Although the neoplasm was poorly responsive to standard chemotherapeutic protocols for lymphoma, radiation therapy rapidly reduced its size. Three years following the initial diagnosis, there has been no recurrence of the conjunctival neoplasm. To the authors' knowledge, there are no previous reports of extranodal or adnexal (conjunctiva, eyelid, orbit) Hodgkin's-like lymphoma in the veterinary literature.

摘要

一只七岁已绝育的雌性家养短毛猫,因右眼结膜炎四个月的病史前来检查。上睑结膜弥漫性肿胀且质地坚硬,使右眼球向下移位,导致眼睑无法完全闭合。右腘淋巴结肿大,其他几个外周淋巴结也肿大。结膜肿胀处的切开活检显示为淋巴样肿瘤,其细胞组成提示具有猫霍奇金样淋巴瘤的特征。尽管该肿瘤对淋巴瘤的标准化疗方案反应不佳,但放射治疗迅速缩小了其大小。初次诊断三年后,结膜肿瘤未复发。据作者所知,兽医文献中此前尚无关于结外或附件(结膜、眼睑、眼眶)霍奇金样淋巴瘤的报道。

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