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结膜淋巴瘤:五只犬和三只猫的免疫表型及预后

Conjunctival lymphoma: immunophenotype and outcome in five dogs and three cats.

作者信息

McCowan Christina, Malcolm Julia, Hurn Simon, O'Reilly Anu, Hardman Chloe, Stanley Robin

机构信息

University of Melbourne Veterinary Clinical Centre, 250 Princes Hwy, Werribee, Melbourne, 3030, Vic., Australia; Veterinary Diagnostics, Biosciences Research Division, Department of Primary Industries, 5 Ring Road, Bundoora, Melbourne, 308, Vic., Australia.

出版信息

Vet Ophthalmol. 2014 Sep;17(5):351-7. doi: 10.1111/vop.12083. Epub 2013 Aug 2.

Abstract

Conjunctival lymphoma is well documented in the medical literature, but veterinary reports are few. We report five cases of canine lymphoma, and three of feline in which the presenting sign was conjunctival involvement. All animals were in apparently good health at the time of presentation, and attended the referring clinic because of conjunctival disease. One dog showed generalized lymphadenopathy at presentation, although the ocular lesion was the reason for consultation, but all other patients were well with no detectable disease beyond the eye. All cats were presented for their ocular disease. All dogs were confirmed to have T-cell tumors, although the histological appearance of these was variable. In contrast, all cats had B-cell tumors. Referring clinicians and owners were contacted for follow-up information. Three dogs had been euthanased within 6 months of diagnosis for deterioration of general health. The remaining two were alive and showed no signs of systemic disease. Two cats had good survival following diagnosis, the other died of lesions that may not be related.

摘要

结膜淋巴瘤在医学文献中有充分记载,但兽医报告较少。我们报告了5例犬淋巴瘤病例和3例猫淋巴瘤病例,其主要症状为结膜受累。所有动物在就诊时外表健康,因结膜疾病前往转诊诊所。一只犬在就诊时出现全身性淋巴结病,尽管眼部病变是就诊原因,但所有其他患者除眼部外均健康,未发现其他疾病。所有猫均因眼部疾病就诊。所有犬均确诊为T细胞肿瘤,尽管其组织学表现各不相同。相比之下,所有猫均患有B细胞肿瘤。我们联系了转诊临床医生和主人以获取随访信息。3只犬在诊断后6个月内因全身健康状况恶化而实施安乐死。其余两只存活,未表现出全身疾病迹象。两只猫在诊断后存活良好,另一只死于可能无关的病变。

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