Brommer Harold, Laasanen Mikko S, Brama Pieter A J, van Weeren P René, Helminen Heikki J, Jurvelin Jukka S
Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Vet Surg. 2006 Apr;35(3):259-66. doi: 10.1111/j.1532-950X.2006.00136.x.
To evaluate an arthroscopic indentation instrument (Artscan 200) for assessment of the health status of equine articular cartilage.
In vitro experiment using equine isolated proximal phalanx (P1) specimens.
P1 specimens from 39 horses (aged 1.5-22 years).
Reproducibility was tested by determination of the coefficient of variation (CV). Dynamic modulus and cartilage degeneration index (CDI) values were measured at 2 predefined sites (site 1, joint margin; site 2, joint center) to assess the accuracy and to evaluate the relation with surface integrity.
CV was 9.0%. A significant decrease in indenter force was identified when dynamic modulus values decreased to <2.5 MPa (range of tested samples 0.9-8.1 MPa) and when CDI values at site 1 increased to >50% (range 5.4-72.8%).
Technique reproducibility was adequate but accuracy was limited. The device identified degeneration-associated decreases in cartilage stiffness only when the mechanical properties of the cartilage were considerably changed.
Usefulness of this indentation instrument during arthroscopic surgery would be limited in the initial phase of OA-like cartilage degeneration, but may yield important information in more advanced OA.
