El-Nahas Ahmed R, Shokeir Ahmed A, El-Assmy Ahmed M, Shoma Ahmed M, Eraky Ibrahim, El-Kenawy Mahmoud R, El-Kappany Hamdy A
Department of Urology, Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.
Urology. 2006 May;67(5):937-41. doi: 10.1016/j.urology.2005.11.025. Epub 2006 Apr 25.
To identify the risk factors implicated in colonic perforation during percutaneous nephrolithotomy.
From 1985 to 2004, 5039 percutaneous nephrolithotomy procedures were performed in our center. Colonic perforation complicated 15 procedures (0.3%). The patient files were retrospectively reviewed for detection of preoperative risk factors as shown by multivariate statistical analysis. The operative details and postoperative course were also studied to determine the time and mode of diagnosis of colonic injury and treatment strategies and outcome.
All injuries were retroperitoneal. The mean patient age was 57 +/- 8.4 years. Of the 15 patients, 11 were men and 4 were women. The left side was affected in 10 patients (66.6%). The right side was injured only in those with horseshoe kidneys or with recurrent disease. Colonic perforation complicated lower caliceal puncture in 12 procedures (80%) and complicated upper caliceal punctures in those with horseshoe kidneys or chronic colonic distension. Significant independent risk factors were advanced patient age and the presence of a horseshoe kidney. The diagnosis was established intraoperatively in 5 patients and postoperatively in 10, 5 of whom presented with colocutaneous fistula. The diagnosis was confirmed with abdominal computed tomography or opacification of the colon during antegrade or retrograde pyelography. Conservative treatment was successful in all but 2 patients who required colostomy.
Significant independent risk factors for colonic perforation during percutaneous nephrolithotomy were advanced patient age and the presence of a horseshoe kidney. Early diagnosis and proper treatment represent the key to minimizing patient morbidity and avoiding serious complications.
确定经皮肾镜取石术期间发生结肠穿孔的相关危险因素。
1985年至2004年,我们中心共进行了5039例经皮肾镜取石术。15例手术(0.3%)并发结肠穿孔。对患者病历进行回顾性分析,以检测多变量统计分析显示的术前危险因素。还研究了手术细节和术后病程,以确定结肠损伤的诊断时间和方式、治疗策略及结果。
所有损伤均为腹膜后损伤。患者平均年龄为57±8.4岁。15例患者中,11例为男性,4例为女性。10例患者(66.6%)左侧受累。右侧仅在马蹄肾或复发性疾病患者中受伤。12例手术(80%)中结肠穿孔并发下盏穿刺,马蹄肾或慢性结肠扩张患者中结肠穿孔并发上盏穿刺。显著的独立危险因素是患者年龄较大和存在马蹄肾。5例患者术中确诊,10例术后确诊,其中5例出现结肠皮肤瘘。通过腹部计算机断层扫描或顺行或逆行肾盂造影时结肠显影确诊。除2例需要结肠造口术的患者外,所有患者保守治疗均成功。
经皮肾镜取石术期间发生结肠穿孔的显著独立危险因素是患者年龄较大和存在马蹄肾。早期诊断和适当治疗是将患者发病率降至最低并避免严重并发症的关键。