Koch A L, Schmidt T M
Department of Biology, Indiana University, Bloomington, IN 47405, USA.
J Mol Evol. 1991 Oct;33(4):297-304. doi: 10.1007/BF02102860.
It is proposed that the energy-transducing system of the first cellular organism and its precursor was fueled by the oxidation of hydrogen sulfide and ferric sulfide to iron pyrites and two [H+] on the outside surface of a vesicle (the cell membrane), with the concomitant reduction of CO or CO2 on the interior. The resulting proton gradient across the cell membrane provides a proton-motive force, so that a variety of kinds of work can be done. It is envisioned as providing a selective advantage for cells capable of harvesting this potential. The proposed reactants for these reactions are consistent with the predicted composition of the Earth's early environment. Modern-day homologs of the ancestral components of the energy-transducing system are thought to be membrane-associated ferredoxins for the extracellular redox reaction, carbon monoxide dehydrogenase for the carbon fixation reaction, and ATPase for the harvesting of the proton gradient. With a source of consumable energy, the cell could drive chemical reactions and transport events in such a way as to be exploited by Darwinian evolution.
有人提出，第一个细胞生物体及其前体的能量转换系统是由硫化氢和硫化铁氧化为黄铁矿以及囊泡（细胞膜）外表面的两个[H⁺]来提供能量的，同时内部的CO或CO₂被还原。由此产生的跨细胞膜的质子梯度提供了质子动力，从而可以完成各种类型的工作。可以想象，这为能够利用这种潜力的细胞提供了一种选择优势。这些反应所提出的反应物与地球早期环境的预测组成是一致的。能量转换系统祖先成分的现代同源物被认为是用于细胞外氧化还原反应的膜结合铁氧化还原蛋白、用于碳固定反应的一氧化碳脱氢酶以及用于利用质子梯度的ATP酶。有了可消耗的能量来源，细胞就可以驱动化学反应和运输过程，从而被达尔文进化论所利用。
