Baldwin Brooke T, Prakash Amy, Fenske Neil A, Messina Jane L
Division of Dermatology and Cutaneous Surgery, University of South Florida College of Medicine, Tampa, Florida 33612, USA.
J Am Acad Dermatol. 2006 May;54(5):899-902. doi: 10.1016/j.jaad.2005.09.007.
Aquagenic syringeal acrokeratoderma is a rare acquired condition characterized by painful symmetric swelling and hypopigmentation of the palms and lateral fingers, which develops after brief exposure to water. Histopathologic examination suggests that an aberration in the eccrine sweat gland apparatus may be the underlying cause of this condition. The "hand-in-the-bucket sign," in which patients arrive in their physician's office with their hand in a bucket of water to more readily demonstrate their lesions, is such a common presentation that it almost can be regarded as pathognomonic. All 12 cases reported to date have been in young females. We report a case of aquagenic syringeal acrokeratoderma in a male with unique histologic findings.
水源性掌跖角化病是一种罕见的后天性疾病，其特征为手掌和手指外侧出现疼痛性对称性肿胀及色素减退，在短暂接触水后发病。组织病理学检查提示，小汗腺装置异常可能是该病的潜在病因。“手浸桶征”指患者到医生办公室时将手浸在一桶水中，以便更清楚地展示其皮损，这是一种非常常见的表现，几乎可视为该病的特征性表现。迄今为止报道的所有12例病例均为年轻女性。我们报告1例男性水源性掌跖角化病病例，该病例具有独特的组织学表现。
