Phenylthiocarbamide: a 75-year adventure in genetics and natural selection.
作者信息
Wooding Stephen
机构信息
Department of Human Genetics, University of Utah, Salt Lake City, Utah 84112-5330, USA.
出版信息
Genetics. 2006 Apr;172(4):2015-23. doi: 10.1093/genetics/172.4.2015.
Abstract
摘要
相似文献
1
Phenylthiocarbamide: a 75-year adventure in genetics and natural selection.苯硫脲：遗传学与自然选择领域75年的探索历程
Genetics. 2006 Apr;172(4):2015-23. doi: 10.1093/genetics/172.4.2015.
2
Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin.TAS2R38和TAS2R16中的功能变异影响非裔美国人高危家庭的酒精消费。
Alcohol Clin Exp Res. 2007 Feb;31(2):209-15. doi: 10.1111/j.1530-0277.2006.00297.x.
3
Human taste genetics.人类味觉遗传学
Annu Rev Genomics Hum Genet. 2005;6:217-35. doi: 10.1146/annurev.genom.6.080604.162340.
4
Phenylthiocarbamide taste threshold distribution among the Rastogis of India.印度拉什托吉人苯硫脲味觉阈值分布情况
Acta Genet Med Gemellol (Roma). 1975;24(1-2):167-8. doi: 10.1017/s112096230002206x.
5
Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide.对苯硫脲味觉敏感度相关人类数量性状位点的定位克隆
Science. 2003 Feb 21;299(5610):1221-5. doi: 10.1126/science.1080190.
6
Genetics of individual differences in bitter taste perception: lessons from the PTC gene.苦味味觉感知个体差异的遗传学：来自苯硫脲（PTC）基因的启示
Clin Genet. 2005 Apr;67(4):275-80. doi: 10.1111/j.1399-0004.2004.00361.x.
7
Association of schizophrenia with the phenylthiocarbamide taste receptor haplotype on chromosome 7q.精神分裂症与7号染色体q臂上苯硫脲味觉受体单倍型的关联。
Psychiatr Genet. 2012 Dec;22(6):286-9. doi: 10.1097/YPG.0b013e32835863f0.
8
The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception.苯基硫脲和丙基硫氧嘧啶苦味感知个体差异的分子基础。
Curr Biol. 2005 Feb 22;15(4):322-7. doi: 10.1016/j.cub.2005.01.047.
9
Evolution of the bitter taste receptor TAS2R38 in colobines.疣猴亚目动物中苦味味觉受体TAS2R38的进化
Primates. 2020 May;61(3):485-494. doi: 10.1007/s10329-020-00799-1. Epub 2020 Feb 1.
10
Computational studies of ligand-receptor interactions in bitter taste receptors.苦味受体中配体-受体相互作用的计算研究。
J Recept Signal Transduct Res. 2006;26(5-6):611-30. doi: 10.1080/10799890600928210.
引用本文的文献
1
Phenome-wide investigation of dietary and health outcomes associated with bitter taste receptor gene TAS2R38.对与苦味受体基因TAS2R38相关的饮食和健康结果进行全表型组研究。
Eur J Nutr. 2025 Jun 11;64(5):218. doi: 10.1007/s00394-025-03718-6.
2
Differential Activation of May Recover Ability to Taste Propylthiouracil for Some AVI Homozygotes.某些 AVI 纯合子的巯甲丙脯酸味觉能力可能通过差异激活得到恢复。
Nutrients. 2024 Apr 30;16(9):1357. doi: 10.3390/nu16091357.
3
Association of Mothers' Genetic Taste Perception to Eating Habits and Its Influence on Early Childhood Caries in Preschool Children: An Analytical Study.母亲的遗传味觉感知与饮食习惯的关联及其对学龄前儿童早期龋齿的影响：一项分析研究。
Int J Clin Pediatr Dent. 2022;15(Suppl 2):S135-S139. doi: 10.5005/jp-journals-10005-2139.
4
Bitter taste receptors: Genes, evolution and health.苦味受体：基因、进化与健康。
Evol Med Public Health. 2021 Oct 13;9(1):431-447. doi: 10.1093/emph/eoab031. eCollection 2021.
5
Tissue-Dependent Expression of Bitter Receptor TAS2R38 mRNA.组织依赖性表达苦味受体 TAS2R38 mRNA。
Chem Senses. 2019 Jan 1;44(1):33-40. doi: 10.1093/chemse/bjy066.
6
Using Animal Models to Determine the Role of Gustatory Neural Input in the Control of Ingestive Behavior and the Maintenance of Body Weight.利用动物模型确定味觉神经输入在摄食行为控制和体重维持中的作用。
Chemosens Percept. 2015 Aug;8(2):61-77. doi: 10.1007/s12078-015-9190-y. Epub 2015 Aug 13.
7
Receptor Polymorphism and Genomic Structure Interact to Shape Bitter Taste Perception.受体多态性与基因组结构相互作用塑造苦味感知。
PLoS Genet. 2015 Sep 25;11(9):e1005530. doi: 10.1371/journal.pgen.1005530. eCollection 2015.
8
Prevalence and Genetic Analysis of Bitter Taste Perception for Phenylthiocarbamide (PTC) Among Some Muslim Populations of Uttar Pradesh, India.印度北方邦部分穆斯林人群中苯硫脲（PTC）苦味感知的患病率及遗传分析
Iran J Public Health. 2014 Apr;43(4):441-52.
9
Genetic Vulnerability to Menthol Cigarette Preference in Women.女性对薄荷醇香烟偏好的遗传易感性。
Nicotine Tob Res. 2015 Dec;17(12):1416-20. doi: 10.1093/ntr/ntv042. Epub 2015 Apr 1.
10
Structure-activity analysis of thiourea analogs as inhibitors of UT-A and UT-B urea transporters.硫脲类似物作为UT-A和UT-B尿素转运体抑制剂的构效关系分析
Biochim Biophys Acta. 2015 May;1848(5):1075-80. doi: 10.1016/j.bbamem.2015.01.004. Epub 2015 Jan 19.
本文引用的文献
1
OBSERVATIONS ON TASTE BLINDNESS.
Science. 1932 May 6;75(1949):497-8. doi: 10.1126/science.75.1949.497.
2
A DINNER DEMONSTRATION OF THRESHOLD DIFFERENCES IN TASTE AND SMELL.
Science. 1935 May 24;81(2108):504-7. doi: 10.1126/science.81.2108.504.
3
UNLIKE REACTION OF DIFFERENT INDIVIDUALS TO FRAGRANCE IN VERBENA FLOWERS.不同个体对马鞭草花中香气的反应不同。
Science. 1918 Sep 20;48(1238):298-9. doi: 10.1126/science.48.1238.298-a.
4
INHERITED TASTE DEFICIENCY.遗传性味觉缺陷
Science. 1931 Aug 7;74(1910):151-2. doi: 10.1126/science.74.1910.151.
5
"TASTE DEFICIENCY" FOR CREATINE.
Science. 1931 Dec 11;74(1928):597-8. doi: 10.1126/science.74.1928.597.
6
Independent evolution of bitter-taste sensitivity in humans and chimpanzees.人类和黑猩猩苦味敏感度的独立进化。
Nature. 2006 Apr 13;440(7086):930-4. doi: 10.1038/nature04655.
7
Genetics of Sensory Thresholds: Individual Taste Reactions for Different Substances.感觉阈值的遗传学：不同物质的个体味觉反应
Proc Natl Acad Sci U S A. 1935 Feb;21(2):84-90. doi: 10.1073/pnas.21.2.84.
8
Genetics of Sensory Thresholds: Variations within Single Individuals in Taste Sensitivity for PTC.感觉阈值的遗传学：个体内部对苯硫脲味觉敏感性的差异
Proc Natl Acad Sci U S A. 1935 Feb;21(2):78-83. doi: 10.1073/pnas.21.2.78.
9
Genetics of Sensory Thresholds: Taste for Phenyl Thio Carbamide.感觉阈值的遗传学：苯硫脲味觉
Proc Natl Acad Sci U S A. 1932 Jan;18(1):120-30. doi: 10.1073/pnas.18.1.120.
10
The Relationship between Chemical Constitution and Taste.化学组成与味道之间的关系。
Proc Natl Acad Sci U S A. 1932 Jan;18(1):115-20. doi: 10.1073/pnas.18.1.115.
Zotero 插件