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新生儿肠道病毒脑膜脑炎中的白质损伤

White matter damage in neonatal enterovirus meningoencephalitis.

作者信息

Verboon-Maciolek M A, Groenendaal F, Cowan F, Govaert P, van Loon A M, de Vries L S

机构信息

Department of Neonatology, University Medical Center, Utrecht, The Netherlands.

出版信息

Neurology. 2006 Apr 25;66(8):1267-9. doi: 10.1212/01.wnl.0000208429.69676.23.

DOI:10.1212/01.wnl.0000208429.69676.23
PMID:16636251
Abstract

The authors report six neonates with enteroviral meningoencephalitis. Five infants presented with prolonged seizures, and one presented with systemic enteroviral disease. Cranial ultrasonography showed increased echogenicity in the periventricular white matter, and MRI confirmed mild to severe white matter damage in all infants, which looked similar to periventricular leukomalacia. Two infants developed cerebral palsy: one was neurologically suspect at age 18 months, and three were developmentally normal.

摘要

作者报告了6例患有肠道病毒性脑膜脑炎的新生儿。5名婴儿出现了长时间惊厥,1名婴儿出现了全身性肠道病毒疾病。头颅超声检查显示脑室周围白质回声增强,MRI证实所有婴儿均有轻度至重度白质损伤,这与脑室周围白质软化症相似。2名婴儿发展为脑瘫:1名在18个月大时神经方面可疑,3名发育正常。

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