Rosell-Ferrer J, Merwa R, Brunner P, Scharfetter H
Departament d'Enginyeria Electrònica, Universitat Politècnica de Catalunya, 08034 Barcelona, Spain.
Physiol Meas. 2006 May;27(5):S271-80. doi: 10.1088/0967-3334/27/5/S23. Epub 2006 Apr 24.
We developed a 14-channel multifrequency magnetic induction tomography system (MF-MIT) for biomedical applications. The excitation field is produced by a single coil and 14 planar gradiometers are used for signal detection. The object under measurement was rotated (16 steps per turn) to obtain a full data set for image reconstruction. We make measurements at frequencies from 50 kHz to 1 MHz using a single frequency excitation signal or a multifrequency signal containing several frequencies in this range. We used two acquisition boards giving a total of eight synchronous channels at a sample rate of 5 MS s(-1) per channel. The real and imaginary parts of DeltaB/B(0) were calculated using coherent demodulation at all injected frequencies. Calibration, averaging and drift cancellation techniques were used before image reconstruction. A plastic tank filled with saline (D = 19 cm) and with conductive and/or paramagnetic perturbations was measured for calibration and test purposes. We used a FEM model and an eddy current solver to evaluate the experimental results and to reconstruct the images. Measured equivalent input noise voltage for each channel was 2 nV Hz(-1/2). Using coherent demodulation, with an integration time of 20 ms, the measured STD for the magnitude was 7 nV(rms) (close to the theoretical value only taking into account the amplifier's thermal noise). For long acquisition times the drift in the signal produced a bigger effect than the input noise (typical STD was 10 nV with a maximum of 35 nV at one channel) but this effect was reduced using a drift cancellation technique based on averaging. We were able to image a 2 S m(-1) agar sphere (D = 4 cm) inside the tank filled with saline of 1 S m(-1).
我们开发了一种用于生物医学应用的14通道多频磁感应断层成像系统(MF-MIT)。激励场由单个线圈产生,14个平面梯度仪用于信号检测。对被测物体进行旋转(每转16步)以获取用于图像重建的完整数据集。我们使用单频激励信号或包含该范围内多个频率的多频信号,在50 kHz至1 MHz的频率下进行测量。我们使用了两块采集板,以每通道5 MS s(-1)的采样率总共提供八个同步通道。在所有注入频率下,使用相干解调计算ΔB/B(0)的实部和虚部。在图像重建之前使用了校准、平均和漂移消除技术。为了校准和测试目的,对一个装有盐水(直径 = 19 cm)且带有导电和/或顺磁扰动的塑料罐进行了测量。我们使用有限元模型和涡流求解器来评估实验结果并重建图像。每个通道测量的等效输入噪声电压为2 nV Hz(-1/2)。使用相干解调,积分时间为20 ms,测量的幅度标准偏差为7 nV(rms)(仅考虑放大器的热噪声时接近理论值)。对于长时间采集,信号漂移产生的影响比输入噪声更大(典型标准偏差为10 nV,一个通道最大为35 nV),但使用基于平均的漂移消除技术可减小这种影响。我们能够对一个直径为4 cm、电导率为2 S m(-1)的琼脂球在装有电导率为1 S m(-1)盐水的罐内成像。