触珠蛋白、疟疾和贫血之间有什么关系？
What is the relationship between haptoglobin, malaria, and anaemia?
作者信息
Rogerson Stephen
机构信息
Department of Medicine, University of Melbourne, Royal Melbourne Hospital, Parkville, Victoria, Australia.
出版信息
PLoS Med. 2006 May;3(5):e200. doi: 10.1371/journal.pmed.0030200. Epub 2006 May 2.
Abstract
Rogerson discusses a new study that found that children with the haptoglobin (Hp) 2-2 genotype had a greater fall in hemoglobin over the malaria season than children with other Hp genotypes.
摘要
罗杰森讨论了一项新研究，该研究发现，与其他触珠蛋白（Hp）基因型的儿童相比，具有Hp 2-2基因型的儿童在疟疾季节期间血红蛋白下降幅度更大。
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本文引用的文献
1
Seasonal childhood anaemia in West Africa is associated with the haptoglobin 2-2 genotype.西非儿童季节性贫血与触珠蛋白2-2基因型有关。
PLoS Med. 2006 May;3(5):e172. doi: 10.1371/journal.pmed.0030172. Epub 2006 May 2.
2
Association of haptoglobin levels with age, parasite density, and haptoglobin genotype in a malaria-endemic area of Gabon.加蓬疟疾流行地区触珠蛋白水平与年龄、寄生虫密度及触珠蛋白基因型的关联
Am J Trop Med Hyg. 2006 Jan;74(1):26-30.
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The clinical and pathophysiological features of malarial anaemia.疟疾性贫血的临床和病理生理特征。
Curr Top Microbiol Immunol. 2005;295:137-67. doi: 10.1007/3-540-29088-5_6.
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Limited influence of haptoglobin genotypes on severe malaria in Ghanaian children.触珠蛋白基因型对加纳儿童重症疟疾的影响有限。
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Erythrocyte variants and the nature of their malaria protective effect.红细胞变体及其疟疾保护作用的本质。
Cell Microbiol. 2005 Jun;7(6):753-63. doi: 10.1111/j.1462-5822.2005.00524.x.
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