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[强调角膜移植术后免疫排斥反应的防治]

[Emphasizing the prevention and treatment of immune rejection after corneal transplantation].

作者信息

Shi Wei-yun, Xie Li-xin

出版信息

Zhonghua Yan Ke Za Zhi. 2006 Jan;42(1):3-5.

Abstract

Corneal transplantation is a major therapeutic method to recover the sight from corneal blindness, however, the immune rejection is still the major impact factor for graft failure. With the improvement of the medical care in our country, corneal transplantation has been increased continually. Therefore, reducing the complications and increasing the long-term transparency rate of the graft is an important mission for ophthalmologists. The key core of the corneal transplantation is to pay more attention to the follow-up and prevent the immune rejection. Three respects, including the current status and problems of corneal transplantation in China, the update immune rejection theory and the means of reducing the immune rejection of the corneal graft, and the methods to reduce the risk of blindness due to immune rejection, will be focused in this paper.

摘要

角膜移植是恢复角膜盲视力的主要治疗方法,然而,免疫排斥仍是导致移植失败的主要影响因素。随着我国医疗水平的提高,角膜移植数量不断增加。因此,减少并发症、提高移植片的长期透明率是眼科医生的一项重要任务。角膜移植的关键核心在于加强随访并预防免疫排斥。本文将重点探讨三个方面,包括我国角膜移植的现状与问题、免疫排斥理论的更新以及降低角膜移植免疫排斥的方法,还有降低因免疫排斥导致失明风险的方法。

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