Asilian Ali, Iraji Fariba, Hedaiti Hamid Reza, Siadat Amir Hossein, Enshaieh Shahla
Department of dermatology, Skin Diseases and Leishmaniasis Research Center, Isfahan University School of Medicine, Iran.
Dermatol Online J. 2006 Feb 28;12(2):3.
We report the use of a carbon dioxide laser to vaporize local cutaneous leishmaniasis. We used CO2 laser for the treatment of 24 patients with lupoid cutaneous leishmaniasis in Isfahan. We identified 24 patients with lupoid cutaneous leishmaniasis (LCL) for evaluation. All of the patients had clinical signs of LCL and had the lesion for more than 1 year. LCL diagnosis was confirmed by both direct smear and biopsy. The efficacy of laser was determined on the basis of cure and lack of relapse after 1 year. Treatment was performed using a CO2 laser (Lasersonic LS500 machine). The maximum power was 100 Watts and the pulse width was 0.5-5 seconds. There were 21 patients, 13 females and 8 males, who were treated and followed for 1 year. Mean duration of the lesions was 4.1+/- 3.9 years. The treatment was well tolerated and complications were minimal, and included pain, xerosis, and mild erythema. Of these patients, 19 were disease free (90.47 % efficacy based on clinic and laboratory). Only 2 patients were treatment failures (9.5 %). Our results indicate that CO2 laser radiation is highly effective for treatment of lupoid cutaneous leishmaniasis.
我们报告了使用二氧化碳激光汽化治疗局部皮肤利什曼病的情况。我们在伊斯法罕使用二氧化碳激光治疗了24例类狼疮性皮肤利什曼病患者。我们确定了24例类狼疮性皮肤利什曼病（LCL）患者进行评估。所有患者均有LCL的临床症状，且病损时间超过1年。LCL诊断通过直接涂片和活检得以证实。激光治疗的疗效是根据1年后的治愈情况和无复发情况来确定的。治疗使用的是二氧化碳激光（Lasersonic LS500机器）。最大功率为100瓦，脉冲宽度为0.5 - 5秒。有21例患者（13名女性和8名男性）接受了治疗并随访了1年。病损的平均时长为4.1±3.9年。治疗耐受性良好，并发症极少，包括疼痛、皮肤干燥和轻度红斑。在这些患者中，19例无疾病（基于临床和实验室检查，有效率为90.47%）。只有2例治疗失败（9.5%）。我们的结果表明，二氧化碳激光辐射对治疗类狼疮性皮肤利什曼病非常有效。
