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头皮脂肪性水肿性脱发

Lipedematous alopecia of the scalp.

作者信息

Piraccini Bianca Maria, Voudouris Stylianos, Pazzaglia Massimiliano, Rech Giulia, Vicenzi Colombina, Tosti Antonella

机构信息

Department of Dermatology, University of Bologna, Via Massarenti 1, 40138-Bologna, Italy.

出版信息

Dermatol Online J. 2006 Feb 28;12(2):6.

Abstract

Lipedematous scalp is a rare disorder, mainly described in adult African-American females. We report 2 adult caucasian males with lipedematous scalp associated with androgenetic alopecia. Patients were studied by dermoscopy and histopathology; they were treated with finasteride 1 mg. In our patients, lipedematous scalp affected the occipital and the vertex areas and pathologically exhibited mild edema and thickening of the adipose subcutaneous layer. At videodermoscopy, lipedematous scalp areas showed linear areas of teleangiectasia within the scalp creases, possibly caused by compression of the superficial blood capillaries by the increased volume of the subcutaneous fat layer within the thickened scalp. Finasteride at a dose of 1 mg per day for 1 year induced mild improvement of androgenetic alopecia in one patient and stabilization of the disease in the other. The lipedematous scalps remain unchanged. Lipedematous scalp is apparently a rare disease even though the condition is probably underdiagnosed. As a matter of fact, we diagnosed lipedematous scalp in our patients during a clinical examination for androgenetic alopecia, which was the patients' complaint. The association of lipedematous scalp and androgenetic alopecia in our two patients appears to be coincidental.

摘要

脂肿性头皮是一种罕见的疾病,主要见于成年非裔美国女性。我们报告了2例患有脂肿性头皮并伴有雄激素性脱发的成年白种男性。对患者进行了皮肤镜检查和组织病理学检查;给予他们1毫克非那雄胺进行治疗。在我们的患者中,脂肿性头皮累及枕部和头顶区域,病理表现为皮下脂肪层轻度水肿和增厚。在视频皮肤镜检查中,脂肿性头皮区域在头皮褶皱内显示出线性毛细血管扩张区,这可能是由于增厚头皮内皮下脂肪层体积增加压迫浅表毛细血管所致。每天服用1毫克非那雄胺,持续1年,1例患者的雄激素性脱发有轻度改善,另1例病情稳定。脂肿性头皮保持不变。脂肿性头皮显然是一种罕见疾病,尽管该病可能未得到充分诊断。事实上,我们是在对患者因雄激素性脱发进行临床检查时诊断出脂肿性头皮的,这是患者的主诉。我们这2例患者中脂肿性头皮与雄激素性脱发的关联似乎是巧合。

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