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主动脉窦瘤

Aneurysm of the sinus of valsalva.

作者信息

Ott David A

机构信息

Division of Cardiovascular Surgery, the Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, TX, USA.

出版信息

Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2006:165-76. doi: 10.1053/j.pcsu.2006.02.014.

Abstract

Aneurysms of the sinus of Valsalva (ASVs) are rare. They can be congenital or acquired through infection, trauma, or degenerative diseases. They frequently co-occur with ventricular septal defects, aortic valve dysfunction, or other cardiac abnormalities. Although unruptured ASVs are usually asymptomatic, ruptured ASVs often cause symptoms similar to those of heart failure and produce a continuous, mechanical-sounding murmur. Transsternal or transesophageal echocardiography is usually effective in detecting ASVs. Because symptomatic ASVs pose significant risks for the patient, and because the repair of asymptomatic ASVs generally produces excellent outcomes, surgery is indicated in most cases. The primary goals of surgical repair are to close the ASV securely, remove or obliterate the aneurysmal sac, and repair any associated defects. Operative mortality is generally low except in patients with concomitant bacterial endocarditis or other infections. Late events are uncommon and tend to be related to aortic valve prothesis or Marfan syndrome.

摘要

主动脉窦瘤(ASV)较为罕见。它们可以是先天性的,也可因感染、创伤或退行性疾病后天形成。它们常与室间隔缺损、主动脉瓣功能障碍或其他心脏异常同时出现。虽然未破裂的主动脉窦瘤通常无症状,但破裂的主动脉窦瘤常引发类似心力衰竭的症状,并产生连续性机械样杂音。经胸或经食管超声心动图通常能有效检测主动脉窦瘤。由于有症状的主动脉窦瘤会给患者带来重大风险,且无症状主动脉窦瘤的修复通常能产生良好效果,所以大多数情况下都建议进行手术。手术修复的主要目标是牢固闭合主动脉窦瘤、切除或消除瘤囊,并修复任何相关缺损。除伴有细菌性心内膜炎或其他感染的患者外,手术死亡率一般较低。晚期事件并不常见,且往往与主动脉瓣人工瓣膜或马方综合征有关。

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