Harada Hirofumi, Kato Toshihiko
Department of Otorhinolaryngology, School of Medicine, Fukuoka University, Fukuoka, Japan.
Int Tinnitus J. 2005;11(2):115-8.
Sudden sensorineural hearing loss (SSNHL) remains a controversial problem with respect to etiology and the factors that might predict prognosis. We used logistical regression analysis to determine which factors are most strongly related to outcome for patients with SSNHL. In so doing, we employed a retrospective chart-review study. The study group consisted of 296 patients (296 ears). The outcome of SSNHL was cured (full recovery) in 64, recovered (partial recovery) in 175, and no change in 57. We performed separate analyses on those in the no-change and partial-recovery groups and on those in the no-change and full-recovery groups. The following factors were studied as explanatory variables: age; number of days until presentation; vestibular symptom; initial mean hearing level at 0.25 kHz, 0.5 kHz, 1 kHz, 2 kHz, and 4 kHz; and treatments (steroids, satellite ganglion block). In the first analysis, for patients in the no-change and recovered groups, the factors most strongly related to outcome were the number of days until presentation and age. The second analysis, for the nochange and cured groups, revealed that the number of days until presentation, vestibular symptom, age, and initial mean hearing level were most strongly related to outcome. Our results will increase the ability to predict the outcome for SSNHL.
突发性感音神经性听力损失（SSNHL）在病因及可能预测预后的因素方面仍是一个存在争议的问题。我们使用逻辑回归分析来确定哪些因素与SSNHL患者的预后最密切相关。在此过程中，我们采用了一项回顾性病历审查研究。研究组由296例患者（296耳）组成。SSNHL的预后情况为：64例治愈（完全恢复），175例好转（部分恢复），57例无变化。我们分别对无变化组和部分恢复组以及无变化组和完全恢复组进行了分析。以下因素作为解释变量进行研究：年龄；就诊前天数；前庭症状；0.25kHz、0.5kHz、1kHz、2kHz和4kHz处的初始平均听力水平；以及治疗方法（类固醇、星状神经节阻滞）。在第一次分析中，对于无变化组和恢复组的患者，与预后最密切相关的因素是就诊前天数和年龄。第二次分析针对无变化组和治愈组，结果显示就诊前天数、前庭症状、年龄和初始平均听力水平与预后最密切相关。我们的研究结果将提高预测SSNHL预后的能力。
