Koch Bernd
Can Fam Physician. 2006 Apr;52(4):466-71.
To review 4 topics in hypoglycemia (HoG) care: diagnosis, circumstances predisposing to HoG, risk of adverse effects, and prevention. QUALITY OF EVIDENCE MEDLINE: was searched using the words hypoglycemia and diabetes mellitus. Other relevant sources were hand searched. Evidence was mostly level III and IV from consensus, from observation, and from the author's clinical experience.
Hypoglycemia can be diagnosed using clinical criteria or using a glucometer; it cannot be diagnosed after death. Capillary blood glucose testing for HoG is required only for patients taking insulin and insulin secretagogues. With intensified treatment of diabetes, a greater incidence of HoG is inevitable. Chronic morbidity and mortality resulting from HoG are believed to be rare. There are no reliable data on HoG-related mortality for idiopathic or accidental sudden death. Interventions by friends, family, colleagues, and teachers can prevent HoG.
Clinical diagnosis of HoG deserves greater emphasis; when patients are unaware of having HoG, physicians must rely on blood glucose testing. Patients not taking insulin or insulin secretagogues need neither fear nor test for HoG. The risk of HoG should not preclude efforts to achieve best possible control of blood sugar. Patients with unstable cardiac arrhythmias, drivers of motor vehicles, and those in high-risk industrial occupations require special vigilance for HoG.
回顾低血糖(HoG)护理中的4个主题:诊断、易发生HoG的情况、不良反应风险及预防。证据质量 通过使用“低血糖”和“糖尿病”等词汇检索医学期刊数据库(MEDLINE)。还对其他相关来源进行了手工检索。证据大多为来自共识、观察及作者临床经验的Ⅲ级和Ⅳ级证据。
低血糖可通过临床标准或血糖仪进行诊断;死后无法诊断。仅对使用胰岛素和胰岛素促泌剂的患者需要进行毛细血管血糖检测以诊断HoG。随着糖尿病治疗的强化,HoG的发生率必然会更高。据信,HoG导致的慢性发病率和死亡率较为罕见。关于特发性或意外猝死与HoG相关的死亡率,尚无可靠数据。朋友、家人、同事和教师的干预可预防HoG。
HoG的临床诊断应得到更多重视;当患者未意识到自己发生HoG时,医生必须依靠血糖检测。未使用胰岛素或胰岛素促泌剂的患者既无需担心也无需检测HoG。HoG的风险不应妨碍为实现血糖最佳控制所做的努力。患有不稳定心律失常的患者、机动车驾驶员以及从事高风险行业工作的人员需要特别警惕HoG。