Ahn Hyo Hyun, Kim Il-hwan
Department of Dermatology, Korea University College of Medicine, Seoul, Korea.
Dermatol Surg. 2006 Mar;32(3):372-5; discussion 375. doi: 10.1111/j.1524-4725.2006.32075.x.
Patients with skin of color demand treatment modality suitable for their skin. Salicylic acid peel has effectiveness for both of acne and postinflammatory hyperpigmentation that are common in patients with skin of color.
To assess the whitening effect of salicylic acid peels in Asian patients with acne objectively by the colorimetric method.
Twenty-four healthy adult patients with acne participated voluntarily in the study. Any other systemic and topical acne treatments were prohibited. They had undergone full-face peels with 30% salicylic acid in absolute ethanol bi-weekly for 3 months. Colorimetric changes of the face were recorded with reflectance spectrophotometer.
Paired comparisons with pretreatment CIE Lab* showed abrupt descent of L* value after first peel (p=.0286). Then there was continued increase of mean L* value, even though the final L* value did not reach a statistically significant level. The mean a* value decreased continually, and the a* values recorded after the second, third, fourth, fifth, and final peel showed significantly lowered levels (p=.0027, .0005, <.0001, <.0001, <.0001).
Salicylic acid peels are beneficial in whitening the face of Asian patients with acne. The whitening effect would be an important factor in choosing the superficial peeling agent for them.
有色人种患者需要适合其皮肤的治疗方式。水杨酸焕肤对痤疮以及有色人种患者中常见的炎症后色素沉着均有效。
通过比色法客观评估水杨酸焕肤对亚洲痤疮患者的美白效果。
24名健康成年痤疮患者自愿参与本研究。禁止进行任何其他全身性和局部性痤疮治疗。他们每两周接受一次用无水乙醇配制的30%水杨酸全脸焕肤,共3个月。用反射分光光度计记录面部的比色变化。
与治疗前的CIE Lab值进行配对比较,首次焕肤后L值急剧下降(p = 0.0286)。然后平均L值持续增加,尽管最终L值未达到统计学显著水平。平均a值持续下降,第二次、第三次、第四次、第五次和最后一次焕肤后记录的a值均显示出显著降低(p = 0.0027、0.0005、<0.0001、<0.0001、<0.0001)。
水杨酸焕肤对亚洲痤疮患者的面部美白有益。美白效果将是为他们选择浅表焕肤剂的一个重要因素。