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[婴儿尿路感染:药物治疗]

[Urinary tract infections in infants: medical management].

作者信息

Cochat P, Cochat N

机构信息

Unité de néphrologie pédiatrique, hôpital Edouard-Herriot, Lyon, France.

出版信息

Pediatrie. 1991;46(6-7):521-6.

PMID:1664085
Abstract

The risks of acute pyelonephritis in infants concern microbial invasion and parenchymal damage. There is a high rate of septicemia and of urinary malformations in children under 1 yr of age; in addition, the kidney is a growing organ with a high risk of scarring. Such parenchymal injury may lead to arterial hypertension, and renal failure when bilateral. Vesicoureteric reflux must be evaluated by ultrasound and cystogram; long-term renal scarring needs to be assessed by scintigraphy or pyelography when children are 7 yr old. Short- and long-term risks could be limited by early intravenous biantibiotherapy.

摘要

婴儿急性肾盂肾炎的风险涉及微生物入侵和实质损害。1岁以下儿童败血症和泌尿系统畸形的发生率很高;此外,肾脏是一个正在生长的器官,有很高的瘢痕形成风险。这种实质损伤可能导致动脉高血压,双侧损伤时可导致肾衰竭。必须通过超声和膀胱造影评估膀胱输尿管反流;7岁儿童时需要通过闪烁扫描或肾盂造影评估长期肾脏瘢痕形成。早期静脉联合抗生素治疗可限制短期和长期风险。

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