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从一名急性白血病患者建立双表型白血病细胞系NALM-19并对其进行鉴定。

Establishment and characterization of a bi-phenotypic leukemic cell line, NALM-19, from a patient with acute leukemia.

作者信息

Matsuo Y, Ariyasu T, Adachi T, Tsubota T, Imanishi J, Minowada J

机构信息

Department of Internal Medicine, Okayama City Hospital.

出版信息

Hum Cell. 1991 Sep;4(3):257-60.

PMID:1664237
Abstract

Based on the immunophenotypic and genotypic findings, this acute leukemia cell line, designated NALM-19, is unique in that a partial expression of both B-cell and myeloid cell features are present in this single clonal leukemic cell population. It is noteworthy that two "normal" EB virus-transformed B cell lines, B239 and B240, (paired with NALM-19) were established from the same leukemic blood.

摘要

基于免疫表型和基因分型结果,这种急性白血病细胞系命名为NALM - 19,其独特之处在于在这个单一克隆白血病细胞群体中同时存在B细胞和髓系细胞特征的部分表达。值得注意的是,从同一白血病血液中建立了两个“正常的”EB病毒转化的B细胞系B239和B240(与NALM - 19配对)。

相似文献

1
Establishment and characterization of a bi-phenotypic leukemic cell line, NALM-19, from a patient with acute leukemia.从一名急性白血病患者建立双表型白血病细胞系NALM-19并对其进行鉴定。
Hum Cell. 1991 Sep;4(3):257-60.
2
Two t(9;22) leukemia cell lines (NALM-24 and NALM-25) with bi-phenotypic characteristics and an EBV-positive B-cell non-leukemia cell line (B262) established from a patient with acute lymphoblastic leukemia.两个具有双表型特征的t(9;22)白血病细胞系(NALM-24和NALM-25)以及一个从急性淋巴细胞白血病患者中建立的EBV阳性B细胞非白血病细胞系(B262)。
Hum Cell. 1991 Dec;4(4):339-42.
3
Bi-phenotypic t(9;22)-positive leukemia cell lines from a patient with acute leukemia: NALM-20, established at the onset; and NALM-21, NALM-22 and NALM-23, established after relapse.一名急性白血病患者的双表型t(9;22)阳性白血病细胞系:发病时建立的NALM - 20;复发后建立的NALM - 21、NALM - 22和NALM - 23。
Hum Cell. 1991 Dec;4(4):335-8.
4
Establishment of novel B-cell precursor leukemia sister cell lines NALM-36 and NALM-37: shift of immunoglobulin phenotype to double light chain positive B-cell.新型B细胞前体白血病姐妹细胞系NALM - 36和NALM - 37的建立:免疫球蛋白表型向双轻链阳性B细胞的转变。
Leuk Res. 2002 Jan;26(1):1-10. doi: 10.1016/s0145-2126(01)00070-4.
5
Establishment and characterization of new pre-B cell leukemia cell line NALM-26.
Hum Cell. 1994 Dec;7(4):221-6.
6
Establishment and characterization of a human leukemic cell line with megakaryocytic features: dependency on granulocyte-macrophage colony-stimulating factor, interleukin 3, or erythropoietin for growth and survival.具有巨核细胞特征的人白血病细胞系的建立与鉴定:生长和存活依赖于粒细胞-巨噬细胞集落刺激因子、白细胞介素3或促红细胞生成素
Cancer Res. 1991 Jan 1;51(1):341-8.
7
Establishment and characterization of a clonal human T-cell line, MKB-1 derived from a patient with acute myeloblastic leukemia.
Hum Cell. 1989 Dec;2(4):423-9.
8
Novel B-cell precursor leukemia sister cell lines, NALM-33 and NALM-34, established from a patient with acute lymphoblastic leukemia.从一名急性淋巴细胞白血病患者身上建立的新型B细胞前体白血病姐妹细胞系,NALM-33和NALM-34。
Leuk Lymphoma. 1999 Nov;35(5-6):513-26. doi: 10.1080/10428199909169616.
9
CD10 and CD44 genes of leukemic cells and malignant cell lines show no evidence of transformation-related alterations.白血病细胞和恶性细胞系的CD10和CD44基因未显示出与转化相关的改变迹象。
J Cell Physiol. 1991 Sep;148(3):414-20. doi: 10.1002/jcp.1041480312.
10
Establishment and characterization of a novel megakaryoblastic cell line, MOLM-1, from a patient with chronic myelogenous leukemia.
Hum Cell. 1991 Sep;4(3):261-4.

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