Matsuo Y, Ariyasu T, Ohmoto E, Kimura I, Minowada J
Fujisaki Cell Center, Hayashibara Biochemical Laboratories, Inc.
Hum Cell. 1991 Dec;4(4):335-8.
Four leukemia cell lines; NALM-20, established at the onset of leukemia and NALM-21, -22 and -23 established at the relapse of the disease were found to be t(9;22)-positive leukemia lines having the biphenotypic feature of B cell and myeloid cell characteristics. In addition, a polyclonal Epstein-Barr virus-transformed normal B cell line, B250, was established from the peripheral blood at the onset of the disease.
四种白血病细胞系；白血病发病时建立的NALM - 20以及疾病复发时建立的NALM - 21、- 22和- 23，被发现是t(9;22)阳性的白血病细胞系，具有B细胞和髓样细胞特征的双表型特征。此外，从疾病发病时的外周血中建立了一种多克隆爱泼斯坦-巴尔病毒转化的正常B细胞系B250。
