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Biochemical genetics of phosphohydrolase polymorphism in Culex pipiens complex.

作者信息

Igbokwe E C, Daniels C M, Braden P

机构信息

Biomedical Research Laboratory, Southern University, Shreveport, Louisiana 71107.

出版信息

Comp Biochem Physiol B. 1991;100(4):759-62. doi: 10.1016/0305-0491(91)90286-m.

DOI:10.1016/0305-0491(91)90286-m
PMID:1664307
Abstract
  1. Single 4th-instar larvae were used in the investigation of alkaline phosphohydrolase (APH) variability in Culex pipiens quinequefasciatus. The genetic basis of isozyme variability was determined from genetic crosses performed with isogenic and hybrid strains of mosquitoes. 2. Isozyme electromorphs presented four enzyme activity zones, three monomorphic and one polymorphic, correspondent with four APH gene loci (aph1, aph2, aph3 and aph4). 3. All isozymes migrated anodically, with aph4 isozymes migrating most rapidly. 4. Enzyme polymorphism was evident only at aph4 locus, with three allozymes present. 5. aph4 allozymes are conditioned by multiple, co-dominant alleles transmitted in a Mendelian manner. 6. Differential frequencies and selection for aph4 alleles and genotypes are suggested by data from genetic crosses.
摘要

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