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围产期获得性人类免疫缺陷病毒感染青年的精神障碍

Psychiatric disorders in youth with perinatally acquired human immunodeficiency virus infection.

作者信息

Mellins Claude Ann, Brackis-Cott Elizabeth, Dolezal Curtis, Abrams Elaine J

机构信息

HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, and Columbia University, New York 10032, USA.

出版信息

Pediatr Infect Dis J. 2006 May;25(5):432-7. doi: 10.1097/01.inf.0000217372.10385.2a.

Abstract

BACKGROUND

Clinical reports from the United States indicate substantive mental health problems in perinatally human immunodeficiency virus (HIV)-infected youth that pose substantial barriers to optimizing their health. This pilot study explores rates and types of psychiatric and substance use disorders, as well as emotional and behavioral functioning in perinatally HIV-infected children and adolescents.

METHODS

Forty-seven perinatally-infected youths (9-16 years of age) and their primary caregivers recruited from a pediatric HIV clinic were interviewed using standardized assessments of youth psychiatric disorders and emotional and behavioral functioning, as well as measures of health and caregiver mental health.

RESULTS

According to either the caregiver or child report, 55% of youths met criteria for a psychiatric disorder. The most prevalent diagnoses were anxiety disorders (40%), attention deficit hyperactivity disorders (21%), conduct disorders (13%), and oppositional defiant disorders (11%). However, the majority of caregivers and children scored in the normative range on the symptom questionnaires on emotional and behavioral functioning. None of the demographic or child health variables or measures of caregiver mental health was significantly associated with presence of a child psychiatric disorder. There was an association between caregiver mental health and child emotional and behavioral functioning.

CONCLUSIONS

Standardized assessments of mental health identified very high rates of psychiatric disorders, primarily in the anxiety and behavioral domains, in this sample of youth with perinatal HIV infection. Mental health interventions should be integrated into medical care to help members of this highly vulnerable population optimize their health and well-being.

摘要

背景

来自美国的临床报告表明,围产期感染人类免疫缺陷病毒(HIV)的青少年存在严重的心理健康问题,这对优化他们的健康构成了重大障碍。这项试点研究探讨了围产期感染HIV的儿童和青少年中精神疾病和物质使用障碍的发生率及类型,以及他们的情绪和行为功能。

方法

从一家儿科HIV诊所招募了47名围产期感染的青少年(9至16岁)及其主要照顾者,使用青少年精神疾病、情绪和行为功能的标准化评估工具,以及健康和照顾者心理健康的测量工具进行访谈。

结果

根据照顾者或儿童的报告,55%的青少年符合精神疾病的标准。最常见的诊断是焦虑症(40%)、注意力缺陷多动障碍(21%)、品行障碍(13%)和对立违抗障碍(11%)。然而,大多数照顾者和儿童在情绪和行为功能症状问卷上的得分处于正常范围。人口统计学或儿童健康变量以及照顾者心理健康测量指标均与儿童精神疾病的存在无显著关联。照顾者心理健康与儿童情绪和行为功能之间存在关联。

结论

心理健康的标准化评估发现,在这个围产期感染HIV的青少年样本中,精神疾病的发生率非常高,主要集中在焦虑和行为领域。心理健康干预应纳入医疗保健中,以帮助这一高度脆弱人群的成员优化他们的健康和福祉。

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