白花岩黄芪中一种新的三萜皂苷——白花苷A的1H和13C核磁共振谱的完整归属

Complete assignments of 1H and 13C NMR spectra of leucanthoside A, a new triterpenoid saponin from Cephalaria leucantha L.

作者信息

Godevac D, Mandić B, Vajs V, Menković N, Macura S, Milosavljević S

机构信息

Institute of Chemistry, Technology and Metallurgy, Njegoseva 12, 11000, Belgrade, Serbia and Montenegro.

出版信息

Magn Reson Chem. 2006 Jul;44(7):731-5. doi: 10.1002/mrc.1834.

DOI:10.1002/mrc.1834

PMID:16645935

Abstract

Leucanthoside A, a new allose-containing triterpenoid saponin (1), was isolated from the aerial parts of Cephalaria leucantha L. Its structure was determined by electrospray ionization mass spectrometry and NMR spectroscopy. Complete assignments of the 1H and 13C NMR chemical shifts were achieved by two-dimensional NMR experiments: DQF-COSY, NOESY, TOCSY, HSQC, DINE-HSQC, HMBC, 13C-1H 2D-J-resolved spectroscopy, and 1,1-ADEQUATE.

摘要

白花苷A是一种新的含阿洛糖三萜皂苷（1），从白花风铃草的地上部分分离得到。其结构通过电喷雾电离质谱和核磁共振光谱确定。通过二维核磁共振实验完成了1H和13C NMR化学位移的完全归属：双量子滤波相关谱（DQF-COSY）、核Overhauser效应谱（NOESY）、全相关谱（TOCSY）、异核单量子相干谱（HSQC）、直接检测异核单量子相干谱（DINE-HSQC）、异核多键相关谱（HMBC）、13C-1H二维J分辨光谱以及1,1-自动检测定量关系谱（1,1-ADEQUATE）。