蒺藜科植物五蕊蒺藜地上部分的甾体皂苷

Steroidal saponins from the aerial parts of Tribulus pentandrus Forssk.

作者信息

Hamed Arafa I, Oleszek Wieslaw, Stochmal Anna, Pizza Cosimo, Piacente Sonia

机构信息

Department of Botany, Faculty of Science, South Valley University, Aswan 81528, Egypt.

出版信息

Phytochemistry. 2004 Nov;65(21):2935-45. doi: 10.1016/j.phytochem.2004.07.003.

DOI:10.1016/j.phytochem.2004.07.003

PMID:15501264

Abstract

Seven new steroidal glycosides named pentandrosides A(1)-G(7) were isolated from the EtOH extract of the aerial parts of Tribulus pentandrus. Pentandrosides A(1)-E(5) possess cholestane aglycones, pentandroside F(6) a furostan-type aglycone and pentandroside G(7) an unusual acyloxypregnane aglycone probably derived from the degradation of a furostan skeleton. Structure elucidation of 1-7 was accomplished through the extensive use of 1D- and 2D NMR experiments including 1H-1H (DQF-COSY, 1D-TOCSY) and 1H-13C (HSQC, HMBC) spectroscopy along with ESIMS and HRESIMS.

摘要

从蒺藜（Tribulus pentandrus）地上部分的乙醇提取物中分离出7种新的甾体糖苷，命名为五雄蕊苷A(1)-G(7)。五雄蕊苷A(1)-E(5)具有胆甾烷苷元，五雄蕊苷F(6)具有呋甾烷型苷元，五雄蕊苷G(7)具有一种不寻常的酰氧基孕甾烷苷元，可能源自呋甾烷骨架的降解。通过广泛使用一维和二维核磁共振实验，包括1H-1H（DQF-COSY、1D-TOCSY）和1H-13C（HSQC、HMBC）光谱以及电喷雾离子质谱（ESIMS）和高分辨电喷雾离子质谱（HRESIMS），完成了对1-7的结构解析。