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[振动病患者神经肌肉系统的临床电生理变化]

[Clinico-electrophysiological changes in the neuromuscular system of patients with vibration disease].

作者信息

Liubimova R P

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1991;91(9):13-7.

PMID:1664604
Abstract

Neuromuscular alterations associated with vibratory disease related to the pathology of spinal motoneurons, axon (degeneration, demyelinization), synapse, muscle. The site, nature and the intensity of the process depended on the duration of work with vibroinstruments, industrial characteristics. During specialized employment, the patients manifested aggravation of the clinical and neurophysiological parameters of the denervation process. Compensatory innervation of the muscles (branching of axon terminals, establishment of new neuromuscular contacts, ets.) was most effective in polishers and riveters. Foundry cleaners demonstrated a tendency toward progress of neuromuscular pathology. To explain motor disorders in patients with vibratory disease, the mechanisms of microtraumatization of nerve endings followed by involvement of the neurotrophic and neuroreflectory systems are suggested.

摘要

与振动病相关的神经肌肉改变涉及脊髓运动神经元、轴突(变性、脱髓鞘)、突触和肌肉的病理变化。该过程的部位、性质和强度取决于使用振动工具的工作时长以及行业特点。在从事特定工作期间,患者的去神经支配过程的临床和神经生理参数会加重。肌肉的代偿性神经支配(轴突终末分支、建立新的神经肌肉连接等)在打磨工和铆工中最为有效。铸造清理工表现出神经肌肉病理变化进展的趋势。为了解释振动病患者的运动障碍,有人提出了神经末梢微创伤机制,随后涉及神经营养和神经反射系统。

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