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[局部振动所致振动病患者运动障碍的发病机制(临床-神经肌电图研究)]

[Pathogenesis of motor disorders in patients with vibration disease caused by local vibration (clinico-electroneuromyographic study].

作者信息

Liubimova R P

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1990;90(10):16-20.

PMID:1962991
Abstract

The author provides the data on clinical, neurophysiological examinations of 195 patients suffering from vibration disease, stages I and II, due to local vibration. Three types of axonal injuries were established: axonal degeneration, demyelinization of the distal part of axon and demyelinization of its proximal part. All the three types of neural disorders were attended by synaptic alterations with a decrement of the M-response and the syndrome of "working in". The initial manifestations of neurophysiological pathology were axonal degenerative disorders with changes in neuromuscular transmission; on longer exposure to vibration there appeared the signs of demyelination. The length of service with vibrating tools is given fr the occupational groups with above-indicated neural disorders. The patterns of motor disorders did not depend on the type of vibrating tools, whereas the localization of the pathological alterations was related to the characteristic features of an industry.

摘要

作者提供了195例因局部振动导致的I期和II期振动病患者的临床及神经生理学检查数据。确定了三种轴索损伤类型:轴索变性、轴索远端脱髓鞘和近端脱髓鞘。所有这三种神经障碍均伴有突触改变,M反应递减及“工作中”综合征。神经生理学病理的初始表现为轴索性变性障碍伴神经肌肉传递改变;长时间接触振动后出现脱髓鞘征象。给出了患有上述神经障碍的职业群体使用振动工具的工作年限。运动障碍模式不取决于振动工具类型,而病理改变的定位与行业特点有关。

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