Liubimova R P
Zh Nevrol Psikhiatr Im S S Korsakova. 1995;95(6):30-6.
The author presents the data of electrophysiologic investigation of distal axon and synaptic structures in patients of different occupations (reveters, choppers, polishers) exposed to medium or high frequency vibration. A correlation analysis of SEMG index relation with the duration of service in confact with vibration showed it to cause two types of defects in neuromuscular transmission: myastenic and "increment" syndrome. The former correlated with vibratoin exposure, the letter--with duration of service. It was suggested to regard two types of synaptic disorders as a denervation reinnervation stage in axons terminals. Compensatory potential of axons is rather small, reinnervation capacities are short-termed and in spite of the absence of degenerative changes of axons advace. Mechanisms of traumatic effect of vibration on synaptic structures responsible for subsequent neuro-reflectory and neuro-trophyc changes of motor neuron of the spinal cord, were assertained according to SEMG, EMG and correlation analysis.
作者展示了不同职业（铆工、伐木工人、打磨工）接触中高频振动患者的远端轴突和突触结构的电生理研究数据。对肌电图（SEMG）指标与接触振动服务时长之间的关系进行相关性分析表明，振动会导致神经肌肉传递出现两种类型的缺陷：肌无力综合征和“递增”综合征。前者与振动暴露相关，后者与服务时长相关。有人建议将这两种类型的突触紊乱视为轴突终末的去神经再支配阶段。轴突的代偿潜力相当小，再支配能力是短期的，尽管轴突没有进行性退变。根据肌电图、肌电图（EMG）和相关性分析，确定了振动对突触结构的创伤作用机制，该机制导致脊髓运动神经元随后发生神经反射和神经营养变化。
