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耳鼻咽喉科中的HIV表现

HIV manifestations in otolaryngology.

作者信息

Prasad H Kishore Chandra, Bhojwani Kiran M, Shenoy Vijendra, Prasad Sampath Chandra

机构信息

Department of Otolaryngology, Head and Neck Surgery, Kasturba Medical College, Mangalore, Karnataka State, India.

出版信息

Am J Otolaryngol. 2006 May-Jun;27(3):179-85. doi: 10.1016/j.amjoto.2005.09.011.

Abstract

PURPOSE

AIDS is a fatal illness, which breaks down the body's immunity and leaves the victim vulnerable to life-threatening opportunistic infections, neurological disorders, or unusual malignancies. About 80% of patients with HIV infections present with otolaryngological symptoms. Often, the otolaryngologist is the primary physician who diagnoses the HIV infection. He should be aware and vigilant for its symptoms and unusual presentations. The aim of our study was to determine the incidence of otolaryngological manifestations, the clinical presentations, relevant diagnostic tools, management, and survival rates.

MATERIALS AND METHODS

We studied 968 patients who were diagnosed to have HIV infection at Kasturba Medical College, Mangalore, India, from January 1996 to December 2004. The incidence of otolaryngological manifestations was noted. Patients with opportunistic infections were treated by specific and symptomatic measures. Of 968 patients studied, 419 were followed up for a 5-year period.

RESULTS

In our study, otolaryngological findings were noted in 79% of individuals. Oropharyngeal findings, which were the commonest, were seen in 59%, followed by cervical lymphadenopathy in 42% of patients. Oral candidiasis was the commonest oropharyngeal finding, seen in 39% of patients. Among nasal complaints, rhinosinusitis was the commonest, found in 17% of patients. Otological manifestations were seen in 20%, of which chronic suppurative otitis media was the commonest, seen in 13% of patients. Routine investigations were found to suffice for diagnosis. Of 419 patients who were followed up, the 5-year survival rate was 73%.

CONCLUSION

With the increase in the number of AIDS cases, it is important for otolaryngologists to be aware of otolaryngological manifestations. Early diagnosis and timely intervention along with appropriate antiretroviral therapy improve survival rates.

摘要

目的

艾滋病是一种致命疾病,它会破坏人体免疫力,使患者易受危及生命的机会性感染、神经紊乱或罕见恶性肿瘤的侵害。约80%的HIV感染者会出现耳鼻喉科症状。通常,耳鼻喉科医生是诊断HIV感染的首诊医生。他应了解并警惕其症状及异常表现。我们研究的目的是确定耳鼻喉科表现的发生率、临床表现、相关诊断工具、治疗方法及生存率。

材料与方法

我们研究了1996年1月至2004年12月在印度芒格洛尔卡斯图尔巴医学院被诊断为HIV感染的968例患者。记录耳鼻喉科表现的发生率。对机会性感染患者采取特异性和对症治疗措施。在研究的968例患者中,419例进行了为期5年的随访。

结果

在我们的研究中,79%的个体有耳鼻喉科检查结果。口咽部表现最为常见,见于5�%的患者,其次是颈部淋巴结病,见于42%的患者。口腔念珠菌病是最常见的口咽部表现,见于39%的患者。在鼻部症状中,鼻窦炎最为常见,见于17%的患者。耳部表现见于20%的患者,其中慢性化脓性中耳炎最为常见,见于13%的患者。发现常规检查足以进行诊断。在接受随访的419例患者中,5年生存率为73%。

结论

随着艾滋病病例数量的增加,耳鼻喉科医生了解耳鼻喉科表现非常重要。早期诊断、及时干预以及适当的抗逆转录病毒治疗可提高生存率。

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